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Showing posts from June, 2021

The Promise of Spatial Transcriptomics in Exploring Chronic Liver Disease

via The Scientist RSS https://ift.tt/3w8VyCf Prakash Ramachandran discusses using spatial transcriptomics to understand liver fibrosis and what he can learn from analyzing biobanked tissue samples. https://ift.tt/eA8V8J June 30, 2021 at 08:34PM

Enhancing the Efficacy of CAR T-Cell Therapies

via The Scientist RSS https://ift.tt/3hjQoOb Jessica Morris will discuss strategies to improve CAR T-cell targeting, activation, and killing capabilities. https://ift.tt/eA8V8J June 29, 2021 at 09:10PM

The Quest for a Universal Coronavirus Vaccine

via The Scientist RSS https://ift.tt/3AaxwKc Scientists are on the hunt for a shot that will protect against not only SARS-CoV-2, but other members of its family that may emerge in the future. https://ift.tt/eA8V8J June 30, 2021 at 01:51AM

Roadmap for Establishing a Hydrogen Supply Chain in the Kansai Area (Japan)

via The Scientist RSS https://ift.tt/362gGze Bringing out the potential of the Kansai area through the conception and implementation of a "hydrogen society". https://ift.tt/eA8V8J June 29, 2021 at 09:30PM

Tips and Tricks for Successful ELISAs

via The Scientist RSS https://ift.tt/3y3SA3o Choose and optimize ELISAs to produce consistent results. https://ift.tt/eA8V8J June 28, 2021 at 08:51PM

COVID-19 Vaccines Work in People with Cancer: Study

via The Scientist RSS https://ift.tt/3gUhn3P Moderna's, Pfizer's, and Johnson & Johnson's shots all offered protection against the virus regardless of cancer type, although slightly less so in people with blood cancer. https://ift.tt/eA8V8J June 25, 2021 at 11:54PM

"Dragon Man" May Replace Neanderthal as Our Closest Relative

via The Scientist RSS https://ift.tt/3gW40jT A massive, well-preserved skull discovered in China in the 1930s belongs to a new species called Homo longi, researchers report, but experts remain skeptical about the evidence. https://ift.tt/eA8V8J June 25, 2021 at 11:52PM

Study that Impregnated Male Rats Stirs Controversy

via The Scientist RSS https://ift.tt/3jf9pUM A combination of approaches, including uterus transplantation and the joining of two animals’ circulatory systems, allowed males to bear pups, according to a preprint. But some experts say the experiments were not justified.   https://ift.tt/eA8V8J June 25, 2021 at 11:10PM

Automating Next-Generation Library Preparation

via The Scientist RSS https://ift.tt/3df0EWW An automated pipetting platform facilitates convenient hands-off, efficient DNA library preparation for next-generation sequencing. https://ift.tt/eA8V8J June 25, 2021 at 09:09PM

Improving Cancer Immunotherapy with Anti-Cancer Adenoviruses

via The Scientist RSS https://ift.tt/3gSUEp2 Researchers use a mesenchymal stromal cell-based vector to deliver multiple viruses simultaneously to improve CAR-T cell anti-tumor activity. https://ift.tt/eA8V8J June 25, 2021 at 07:07PM

“Lemon Frost” Leopard Geckos’ Cancers Similar to Human Melanomas

via The Scientist RSS https://ift.tt/3wWl8LY The color morph’s bright yellow hue and its propensity for skin tumors both likely stem from a gene implicated in a dangerous form of human skin cancer, suggesting the animals could make an ideal model for studying the disease. https://ift.tt/eA8V8J June 25, 2021 at 02:16AM

Endocrinologist Jean Wilson Dies at 88

via The Scientist RSS https://ift.tt/3jeO2CS The University of Texas Southwestern professor's research focused on the androgen hormones that cause male sexual differentiation and may also lead to prostate disease. https://ift.tt/eA8V8J June 25, 2021 at 01:47AM

Scientists Go Down the Cicada Hole

via The Scientist RSS https://ift.tt/2SUjOul Brood X's emergence tunnels—numbering in the hundreds per square meter of soil—give researchers a special opportunity to study how such extreme soil aeration affects the ecosystem. https://ift.tt/eA8V8J June 25, 2021 at 01:45AM

New Study Fuels Debate About Source of Birds' Magnetic Sense

via The Scientist RSS https://ift.tt/3dajsGR A detailed analysis of cryptochrome 4 shows that the protein is highly sensitive to magnetic fields in vitro, but some researchers dispute the authors' assertion that the findings help explain avian magnetoreception. https://ift.tt/eA8V8J June 24, 2021 at 02:50AM

Maternal Vaginal Fluids Mimic Microbe Transfer of Vaginal Birth

via The Scientist RSS https://ift.tt/3xHAPX6 Swabbing infants born by Cesarean-section with a gauze harboring their mother’s vaginal fluids made their skin and gut microbiota more closely resemble that of vaginally born babies. https://ift.tt/eA8V8J June 24, 2021 at 02:05AM

Canadian Official Reprimanded for Withholding Winnipeg Lab Info

via The Scientist RSS https://ift.tt/3h2hkBW The House of Commons rebuked the president of the Canadian Public Health Agency for not turning over sensitive information pertaining to the dismissal of government scientists from the National Microbiology Laboratory. https://ift.tt/eA8V8J June 24, 2021 at 12:10AM

Detecting Methylation with a Highly Sensitive Workflow

via The Scientist RSS https://ift.tt/3qiRKNd Enzymatic conversion and hybrid capture target enrichment combine to optimize methylation sequencing. https://ift.tt/eA8V8J June 22, 2021 at 11:23PM

John Pawelek, Who Explored the Causes of Metastasis, Dies at 79

via The Scientist RSS https://ift.tt/3vOJcPw The Yale School of Medicine cancer researcher doggedly pursued the question of how cancer spreads. https://ift.tt/eA8V8J June 22, 2021 at 10:11PM

Special Straw May Be Reliable Cure for Hiccups: Study

via The Scientist RSS https://ift.tt/3wORbNH The device helps control diaphragm contractions, preventing hiccup-causing muscle spasms. https://ift.tt/eA8V8J June 22, 2021 at 02:14AM

Pipe Dreams TS Book Club Discussion

via The Scientist RSS https://ift.tt/3zIUgRu Join The Scientist on August 20 to discuss Chelsea Wald’s tour of projects aimed at improving toilets—and solving many of the world’s problems in the process. https://ift.tt/eA8V8J June 19, 2021 at 01:20AM

African Coelacanths May Live to Be 100: Study

via The Scientist RSS https://ift.tt/35zA32v This evolutionarily ancient fish species has a lifespan that's around five times longer than previously thought, and a gestation time of more than five years. https://ift.tt/eA8V8J June 19, 2021 at 01:30AM

Chimp Groups Have Their Own Distinct "Handshakes"

via The Scientist RSS https://ift.tt/3gCllOA A 12-year study shows variation among primate groups in how the animals clasp hands during grooming, but consistency within them, even as group membership shifts over time. https://ift.tt/eA8V8J June 19, 2021 at 12:23AM

Pandemic Pressures May Drive Young Scientists Away from Autism Research

via The Scientist RSS https://ift.tt/3gAAsIe For researchers who work with study participants in person, lockdowns made it impossible to obtain fresh data, a survey finds. https://ift.tt/eA8V8J June 19, 2021 at 12:02AM

Q&A: Human Challenge Studies of COVID-19 Underway in UK

via The Scientist RSS https://ift.tt/3gAPs9a Researchers at Imperial College London and the University of Oxford are exposing healthy volunteers to SARS-CoV-2 for science. https://ift.tt/eA8V8J June 18, 2021 at 09:14PM

Aquarium Jellyfish Turns Out to Be Undescribed Species

via The Scientist RSS https://ift.tt/3cNi0da The newly characterized "elegant jellyfish" roughly the size of a human hand, had been on display in two aquariums in Japan for more than a decade. https://ift.tt/eA8V8J June 18, 2021 at 05:43PM

New Evidence Shows COVID-19 Was in US Weeks Before Thought

via The Scientist RSS https://ift.tt/3wCC0Hd Some of the blood specimens collected in the United States for the NIH's All of Us research program starting on January 2, 2020, have antibodies against SARS-CoV-2. https://ift.tt/eA8V8J June 18, 2021 at 12:51AM

Cancer Metastasizes Via Fusion of Tumor and Immune Cells: Study

via The Scientist RSS https://ift.tt/3vwVz2p Researchers say evidence of hybridization between leukocytes and cancer indicates that this is a primary means of metastasis. Others disagree. https://ift.tt/eA8V8J June 17, 2021 at 10:43PM

Improving Ergonomics Reduces Contamination Risk in Microbiological QC Workflows

via The Scientist RSS https://ift.tt/3cI8vvV Making filtration devices easier to clean reduces fatigue and injury risk while improving reproducibility. https://ift.tt/eA8V8J June 17, 2021 at 02:22AM

Highly Multiplexed Cytokine Analysis in Small Animal Models

via The Scientist RSS https://ift.tt/35wm91b New cytokine analysis technology advances cancer therapeutics and vaccine development. https://ift.tt/eA8V8J June 17, 2021 at 01:53AM

Detecting SARS-CoV-2 in Wastewater with qPCR

via The Scientist RSS https://ift.tt/3zwKfXl Special steps are needed to optimize qPCR results for wastewater analysis and surveillance. https://ift.tt/eA8V8J June 17, 2021 at 01:27AM

A Newly Found Organ for Arabidopsis

via The Scientist RSS https://ift.tt/3wBhAyC Horizontal arms dubbed cantils only appear under certain growing conditions--perhaps explaining why they had not been identified before. https://ift.tt/eA8V8J June 17, 2021 at 12:17AM

Introducing Cell Culture Application-Specific Fetal Bovine Serum Products

via The Scientist RSS https://ift.tt/3xrrH97 A cost-effective fetal bovine serum product line is tailored for individual cell culture needs. https://ift.tt/eA8V8J June 16, 2021 at 01:46AM

Deadly Facial Tumors Spur Tasmanian Devil Evolution: Study

via The Scientist RSS https://ift.tt/3gFvuZA The largest study to date of the animals' genetics provides robust evidence that they are adapting to survive a highly lethal, contagious cancer scientists feared would cause their extinction. https://ift.tt/eA8V8J June 16, 2021 at 09:25PM

An integrated system rapidly measures DNA and RNA without sample loss.

via The Scientist RSS https://ift.tt/3zyRM7Q An integrated system rapidly measures DNA and RNA without sample loss. https://ift.tt/eA8V8J June 16, 2021 at 08:18PM

Vitamin D Deficiency Drives Opioid Addiction in Mice

via The Scientist RSS https://ift.tt/3cNvCVP Mice with low vitamin D had exaggerated craving for opioids and felt the drugs' effects more strongly—results supported in part by human medical records—suggesting that supplements should be explored as treatments for opioid use disorders. https://ift.tt/eA8V8J June 16, 2021 at 07:30PM

Clinical Antibody Development: A Journey of Discovery

via The Scientist RSS https://ift.tt/3gINx1g From identifying targets to testing lead candidates, developing antibodies into clinical therapies is a process full of twists and turns. https://ift.tt/eA8V8J June 16, 2021 at 06:14PM

Threads Embedded in Pads and Tampons Can Diagnose Yeast Infection

via The Scientist RSS https://ift.tt/2SCUqJ9 The material turns bright pink when it comes in contact with an enzyme produced by the fungus Candida albicans. https://ift.tt/eA8V8J June 16, 2021 at 01:16AM

Spike Protein Deletions Linked to COVID-19 Surges: Preprint

via The Scientist RSS https://ift.tt/35l0UPQ Researchers find that surges in COVID-19 case numbers are associated with deletions in the SARS-CoV-2 genome in an antigenic site of the spike protein. Some of these mutations are present in vaccine breakthrough infections or reinfections. https://ift.tt/eA8V8J June 16, 2021 at 12:56AM

Glucometers Detect SARS-CoV-2 Infection Within an Hour

via The Scientist RSS https://ift.tt/3grywSt Glucometers are easy-to-use, cheap, and highly scalable. And they are 100 percent accurate at detecting SARS-CoV-2. https://ift.tt/eA8V8J June 14, 2021 at 10:48PM

Skin Rash May Point to SARS-CoV-2 Infection

via The Scientist RSS https://ift.tt/3gGGCFQ Skin symptoms are often the first, or only, symptom of COVID-19. https://ift.tt/eA8V8J June 14, 2021 at 10:38PM

Immune Cell Activity Mediates Severe COVID-19 Pathogenesis

via The Scientist RSS https://ift.tt/3goWX2H Functional profiling of immune cells uncovers targetable mechanisms underlying lung inflammation in severe COVID disease. https://ift.tt/eA8V8J June 15, 2021 at 07:38PM

Reaching Greater PCR Speeds, Specificity, and Fidelity

via The Scientist RSS https://ift.tt/2TvLANx https://ift.tt/eA8V8J June 15, 2021 at 02:26AM

Hawaii Legislature Moves to Terminate Tenured Professor

via The Scientist RSS https://ift.tt/3gxpNgp Carl-Wilhelm Vogel could lose his position at the University of Hawai‘i Cancer Center if the currently proposed state budget is signed by Governor David Ige. https://ift.tt/eA8V8J June 15, 2021 at 05:32PM

Transforming Multichannel Pipettes

via The Scientist RSS https://ift.tt/355xl4L Multichannel pipettes with adjustable tip spacing increase the efficiency and reproducibility of high-throughput experiments. https://ift.tt/eA8V8J June 15, 2021 at 05:30PM

Sexual Harassment Complaints in Academia Are Up Since 2018

via The Scientist RSS https://ift.tt/3gC9izF The NIH shared new data detailing complaints it has received in recent years, the latest in a series of steps taken by funding agencies and professional organizations to address misconduct. https://ift.tt/eA8V8J June 15, 2021 at 03:03AM

Reaching Greater PCR Speeds, Specificity, and Fidelity

via The Scientist RSS https://ift.tt/3pQVAgz https://ift.tt/eA8V8J June 15, 2021 at 02:26AM

Inhaled Antibody Fragments Protect Infected Animals Against COVID-19

via The Scientist RSS https://ift.tt/3wraqwB https://ift.tt/eA8V8J June 14, 2021 at 10:46PM

Survey Finds Lack of Diversity Among Journal Editors

via The Scientist RSS https://ift.tt/2U6OjgL Collecting data on the various races, sexual orientations, and gender identities of editors at 25 scientific and medical journals, researchers document the underrepresentation of minority groups. https://ift.tt/eA8V8J June 14, 2021 at 07:20PM

Nobel Laureate Richard Ernst Dies at 87

via The Scientist RSS https://ift.tt/2SsNRJd The chemist refined nuclear magnetic resonance technology, giving rise to the development of MRI. https://ift.tt/eA8V8J June 12, 2021 at 02:23AM

Why Turkey's Sea of Marmara Is Full of Marine Snot

via The Scientist RSS https://ift.tt/3gqZecL Turkish officials are scrambling to clean up a massive, gooey plankton bloom that's sliming the country's ports and could suffocate the area's marine ecosystems. https://ift.tt/eA8V8J June 12, 2021 at 01:55AM