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Showing posts from July, 2021

Texas Monkeypox Case Underscores Need for Better Surveillance

via The Scientist RSS https://ift.tt/2V8BQdl A patient caught the rare disease in Nigeria before flying through two US airports, exposing more than 200 people from 27 states. https://ift.tt/eA8V8J July 30, 2021 at 11:57PM

Defining Cell Culture Lines and Media

via The Scientist RSS https://ift.tt/3f9xR6Y A new partnership opens the door for a source of highly purified human cell lines and defined cell culture media. https://ift.tt/eA8V8J July 29, 2021 at 08:34PM

Monitoring Organoid Growth in Real Time

via The Scientist RSS https://ift.tt/3ydLFF2 Automated live-cell analysis simplifies organoid research. https://ift.tt/eA8V8J July 30, 2021 at 07:53PM

p53 Unleashes Endogenous Retroviruses to Tackle Tumors: Study

via The Scientist RSS https://ift.tt/37811z3 New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system. https://ift.tt/eA8V8J July 30, 2021 at 02:09AM

Groundbreaking Sleep Researcher J. Allan Hobson Dies at 88

via The Scientist RSS https://ift.tt/3BTt7fy He famously contradicted Sigmund Freud's views on the meaning of dreams. https://ift.tt/eA8V8J July 30, 2021 at 01:57AM

Gut Microbes Help Coordinate Immune Activity in Mice

via The Scientist RSS https://ift.tt/3rFADG6 The microbiota helps align a mouse's innate immune system with its feeding patterns, prepping the animal to fend off infection when it's most likely to be eating. https://ift.tt/eA8V8J July 30, 2021 at 01:40AM

Pure and Simple: Water Quality Determines Experimental Sensitivity

via The Scientist RSS https://ift.tt/3fb0TDk Reliably detect trace amounts of chemicals in complex samples. https://ift.tt/eA8V8J July 30, 2021 at 12:13AM

Preparing Sensitive and Accurate NGS Libraries

via The Scientist RSS https://ift.tt/3BUGeNC https://ift.tt/eA8V8J July 30, 2021 at 12:11AM

Preparing Sensitive and Accurate NGS Libraries

via The Scientist RSS https://ift.tt/3ia0VwZ Reliably detect rare variants with unique molecular identifiers. https://ift.tt/eA8V8J July 29, 2021 at 10:34PM

A Guide to Biobank Storage

via The Scientist RSS https://ift.tt/3zP2OFv Choose the right temperature and storage product for each type of specimen. https://ift.tt/eA8V8J July 29, 2021 at 09:32PM

Low-Abundance Serum Proteins as Biomarkers for Cardiovascular Disease

via The Scientist RSS https://ift.tt/3j04u8v Using deoxyoligonucleotides to bind proteins with high sensitivity and specificity https://ift.tt/eA8V8J July 29, 2021 at 08:40PM

Citing Safety, French Institutions Temporarily Halt Prion Research

via The Scientist RSS https://ift.tt/3zKe1Hl The three-month moratorium comes after a former prion researcher was diagnosed with Creutzfeldt-Jakob disease. https://ift.tt/eA8V8J July 29, 2021 at 02:40AM

890-Million-Year-Old Fossils Are Sponges, Oldest Animals: Study

via The Scientist RSS https://ift.tt/3rNkjU0 If confirmed, the findings indicate that animals appeared on Earth millions of years earlier than previously believed. https://ift.tt/eA8V8J July 29, 2021 at 01:40AM

A "Climate Catastrophe": Western US Salmon on the Brink

via The Scientist RSS https://ift.tt/3rFd8gv A recent sampling from two California streams found nearly all juvenile salmon were infected with deadly parasites, and conditions are expected to worsen. https://ift.tt/eA8V8J July 28, 2021 at 04:32AM

Biogen Defends Newly Approved Alzheimer's Drug

via The Scientist RSS https://ift.tt/3flR2uH The US Food and Drug Administration has called for a federal investigation of its own regulatory review process after widespread criticism of its decision on Aduhelm. https://ift.tt/eA8V8J July 28, 2021 at 01:30AM

US Moves to Drop Visa Fraud Charges Against Chinese Researchers

via The Scientist RSS https://ift.tt/3rBfdKd The scientists were arrested last summer for allegedly hiding or falsifying information about their affiliations with the Chinese military. https://ift.tt/eA8V8J July 27, 2021 at 02:55AM

CDC Warns of Person-to-Person Transmission of Resistant Fungus

via The Scientist RSS https://ift.tt/2TzM9WW In a first, patients who hadn’t been treated with antifungals were found to carry Candida auris impervious to all three available classes of the drugs. https://ift.tt/eA8V8J July 27, 2021 at 12:33AM

Predictions of Most Human Protein Structures Made Freely Available

via The Scientist RSS https://ift.tt/2WfZ29N The AlphaFold program from AI firm DeepMind has amassed a huge database of protein structures from humans and model organisms. https://ift.tt/eA8V8J July 24, 2021 at 02:51AM

How the Second mRNA Vaccine Bolsters Immunity

via The Scientist RSS https://ift.tt/3zIGrSj A study looks beyond T and B cell responses to show how the Pfizer COVID-19 vaccine elicits a strong innate immune response. https://ift.tt/eA8V8J July 24, 2021 at 02:46AM

How to Remove Impurities from Lab Water

via The Scientist RSS https://ift.tt/3kPE63K Measuring volatile organic compounds requires pure water. https://ift.tt/eA8V8J July 23, 2021 at 09:37PM

Form Determines Function: Insights from Structural Biology

via The Scientist RSS https://ift.tt/36TOIq3 Researchers use diverse tools to analyze protein structures. https://ift.tt/eA8V8J July 23, 2021 at 08:37PM

Accelerating qPCR Set-Up with Automated Pipetting

via The Scientist RSS https://ift.tt/3wY2L8n How electronic pipettes and pipetting robots can streamline qPCR set-up for faster and more reproducible results https://ift.tt/eA8V8J July 23, 2021 at 08:27PM

Into the Mind of Human’s Best Friend: Using fMRI to Study Canine Cognition

via The Scientist RSS https://ift.tt/3iGd3VJ Gregory Berns discusses training dogs to undergo fMRI scans to better understand their brains. https://ift.tt/eA8V8J July 23, 2021 at 08:18PM

How Laboratory Testing Supports Clinical Trials

via The Scientist RSS https://ift.tt/3y08o7x Explore the importance of histology and biomarker evaluation for oncology clinical trials. https://ift.tt/eA8V8J July 23, 2021 at 08:00PM

How Laboratory Testing Supports Clinical Trials

via The Scientist RSS https://ift.tt/3hZcEib https://ift.tt/eA8V8J July 23, 2021 at 08:00PM

Optical Genome Mapping Works Well in Detecting Cancer Risk

via The Scientist RSS https://ift.tt/2V0UuU2 The relatively new technique for visually detecting chromosomal variants associated with disease risk performs at least as well as more established techniques in two recent studies. https://ift.tt/eA8V8J July 23, 2021 at 06:02AM

Retinal Activity Prepares Blind Newborn Mice for Vision

via The Scientist RSS https://ift.tt/2UDybnx Spontaneous waves of nerve impulses flowing across the retina help mouse pups practice motion detection for when they eventually open their eyes. https://ift.tt/eA8V8J July 22, 2021 at 11:30PM

How Early-Morning Light Exposure Makes Mice Less Depressed

via The Scientist RSS https://ift.tt/3iCcYlV A light-sensitive gene involved in regulating the body clock may also influence mood, mediating the effect of light. https://ift.tt/eA8V8J July 22, 2021 at 06:06PM

Bacterial Infections Disrupt Flies' Sense of Smell

via The Scientist RSS https://ift.tt/3kH8InP The temporary loss of olfaction stops the flies from eating any more of whatever it is that made them sick. https://ift.tt/eA8V8J July 22, 2021 at 02:30AM

Hawai‘i Legislature Terminates Tenured Professor’s Position

via The Scientist RSS https://ift.tt/3zpv2Gu Thanks to administrative shuffling, professor Carl-Wilhelm Vogel remains employed at the University of Hawai‘i despite the removal of his position in the new state budget, but the university’s faculty union says lawmakers might have crossed a legal line. https://ift.tt/eA8V8J July 22, 2021 at 01:16AM

Push to Address Long-Standing Challenges for Parents in STEMM

via The Scientist RSS https://ift.tt/3hWbELm The organizers behind a Mothers in Science conference say that it’s time academia provide more support to researchers who are pregnant or looking after children. https://ift.tt/eA8V8J July 21, 2021 at 06:45PM

Australian Research Faces Impending Scarcity of Lab Rodents

via The Scientist RSS https://ift.tt/3wQJJ3J The Australian biomedical research community is stunned by the announced wind-down of the country's biggest supplier of mice and rats. https://ift.tt/eA8V8J July 20, 2021 at 10:44PM

Mapping Neuronal Gene Expression to Understand Pain

via The Scientist RSS https://ift.tt/36AWZix Ted Price, Diana Tavares-Ferreira, and Stephanie Shiers discuss how mapping gene expression at the neuronal level provides insight into pain mechanisms and anti-pain drug development. https://ift.tt/eA8V8J July 15, 2021 at 10:49PM

Undone Proteins Take Out Bladder Cancer

via The Scientist RSS https://ift.tt/2Uok5Xc An unfolded protein found in human milk shows promise in early clinical trials to treat bladder cancer. https://ift.tt/eA8V8J July 20, 2021 at 06:45PM

Researchers Find DNA "Borgs" in Methane-Chomping Archaea

via The Scientist RSS https://ift.tt/3x2lrUR Massive extrachromosomal elements named after the hive-minded cyborg villains in Star Trek may be the first of their kind. https://ift.tt/eA8V8J July 20, 2021 at 06:30PM

Homing Technology Delivers Therapy to Cancerous Bone

via The Scientist RSS https://ift.tt/3wRkn66 A clever approach to modifying already existing cancer therapies may be a game changer for treating metastatic breast cancer. https://ift.tt/eA8V8J July 19, 2021 at 10:22PM

Homing Technology Delivers Therapy to Cancerous Bone

via The Scientist RSS https://ift.tt/3eBrp8J https://ift.tt/eA8V8J July 19, 2021 at 10:22PM

Of Guidelines and Gatekeepers: Reproducibility in Flow Cytometry

via The Scientist RSS https://ift.tt/3ilkHVk Guidelines and built-in safeguards ensure the reproducibility of flow cytometry data. https://ift.tt/eA8V8J July 19, 2021 at 09:36PM

Analyzing Biological Systems with Flow Cytometry

via The Scientist RSS https://ift.tt/3rmGkIN Single-cell analysis provides a superior view of heterogeneous cell populations. https://ift.tt/eA8V8J July 19, 2021 at 08:39PM

Humans Can Survive Without Key Autophagy Gene

via The Scientist RSS https://ift.tt/36NuI8h Loss of the protein ATG7 is fatal in mice, but not always for people—although it is linked to human neurodevelopmental disorders, researchers report. https://ift.tt/eA8V8J July 19, 2021 at 07:25PM

Cross-Resistance: One Cancer Therapy Can Undermine the Next

via The Scientist RSS https://ift.tt/3ilk79U Targeted cancer therapy may jeopardize the effectiveness of subsequent immunotherapy by reducing dendritic cell numbers and activation, according to study of mice and patient samples. https://ift.tt/eA8V8J July 16, 2021 at 07:35PM

Human Protein Dissolves Bacterial Membranes

via The Scientist RSS https://ift.tt/3rdFJcn The protein, apolipoprotein L3, destroys invading microbes by acting as a detergent in the cytosol. https://ift.tt/eA8V8J July 16, 2021 at 01:41AM

Opinion: Consult Researchers When Designing Lab Buildings

via The Scientist RSS https://ift.tt/3BaFZgT Disconnects between end users and architects create additional costs and suboptimal design decisions. Here's how to rectify that. https://ift.tt/eA8V8J July 16, 2021 at 12:11AM

Mapping Neuronal Gene Expression to Understand Pain

via The Scientist RSS https://ift.tt/3yZTsGy https://ift.tt/eA8V8J July 15, 2021 at 10:49PM

Australian Beetles Walk on the Underside of Water's Surface

via The Scientist RSS https://ift.tt/3idqo7M Watch one scurry around upside down in a remarkably unusual form of locomotion. https://ift.tt/eA8V8J July 15, 2021 at 10:39PM

Cell Sorting for Single-Cell Applications

via The Scientist RSS https://ift.tt/2UJKMFs Karen Ersland and Rachael Sheridan discuss how flow cytometry contributes to single-cell applications, from cloning to sequencing. https://ift.tt/eA8V8J July 14, 2021 at 08:49PM

My Daughter’s First Pet—the Next Big Model Organism?

via The Scientist RSS https://ift.tt/3xK6g3J Bettas were likely the first fish welcomed into human homes. Now, scientists are welcoming them into the lab to learn how genes dictate their appearance and behavior. https://ift.tt/eA8V8J July 15, 2021 at 09:40PM

Antibiotic-Linked Antibody Attacks Cancer’s Sinister Neighbor Cells

via The Scientist RSS https://ift.tt/3kkkkNg An unexpected and unprecedented finding may lead to improved cancer therapies. https://ift.tt/eA8V8J July 15, 2021 at 04:22AM

Encouraging Digital Laboratory Management Solutions

via The Scientist RSS https://ift.tt/3eCEBu7 A cloud-based platform enables researchers to effectively manage their laboratories. https://ift.tt/eA8V8J July 15, 2021 at 03:41AM

US House Committee Proposes Increases to Research Funding

via The Scientist RSS https://ift.tt/2TdYwba Although many of the spending increases are less than what the Biden administration had requested, the draft legislation calls for a boost in spending for agencies like NASA, the National Institutes of Health, and the Department of Energy. https://ift.tt/eA8V8J July 15, 2021 at 05:41AM