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Showing posts from August, 2021

Gut Microbiome May Help or Hinder Defenses Against SARS-CoV-2

via The Scientist RSS https://ift.tt/3t2D2vf The health of the microbial community is associated with COVID-19 severity, but it's not yet clear if the relationship is causal. https://ift.tt/eA8V8J August 31, 2021 at 05:51PM

Researchers in Ida's Destructive Path Brace for Disruptions

via The Scientist RSS https://ift.tt/2YcIH6H The storm, which made landfall over the weekend as a Category 4 hurricane and has since weakened, forced the evacuation of multiple Louisiana campuses. https://ift.tt/eA8V8J August 31, 2021 at 02:47AM

Immunologist Thomas Hodge Dies of COVID-19 at 69

via The Scientist RSS https://ift.tt/3jv4YVE A former academic and consultant, Hodge cofounded the CrisiScience Collective to help combat the pandemic. https://ift.tt/eA8V8J August 30, 2021 at 08:50PM

Fecal Transplant Restores Youth to Old Mice

via The Scientist RSS https://ift.tt/3ztsDuY Microbiota from young mice reversed some aspects of aging and enhanced brain health in aged mice. https://ift.tt/eA8V8J August 30, 2021 at 07:32PM

Gut Bugs May Help Centenarians Reach Their 100th Birthdays

via The Scientist RSS https://ift.tt/3BjxDTs Centenarians have distinct microbiomes with species that produce unique bile acids, which may help thwart illness. https://ift.tt/eA8V8J August 30, 2021 at 07:25PM

7,200-Year-Old Skeleton Offers Clues to Early Human Migration

via The Scientist RSS https://ift.tt/2V2prYs Analysis of DNA from remains found in an Indonesian cave provides new insight into human movements among the islands between East Asia and Australia. https://ift.tt/eA8V8J August 29, 2021 at 09:54PM

Maurice Taieb, Geologist Who Discovered "Lucy" Site, Dies at 86

via The Scientist RSS https://ift.tt/38kztqI Taieb recognized the potential importance of the Hadar Formation, where remains of the hominin Australopithecus afarensis were found only a few years later. https://ift.tt/eA8V8J August 28, 2021 at 02:45AM

Uncovering Ancient Residual DNA

via The Scientist RSS https://ift.tt/3jp9uVD A look at how ancient events crafted modern human DNA and their potential impact on human health. https://ift.tt/eA8V8J August 27, 2021 at 10:24PM

Tool Would Use Tumor Gene Expression to Inform Radiation Dose

via The Scientist RSS https://ift.tt/3gDEVK0 In a retrospective analysis, a team found that an algorithm integrating the gene expression of a tumor with the radiation dose a patient received predicted how well the patient responded to the treatment. https://ift.tt/eA8V8J August 27, 2021 at 09:31PM

Miniaturizing Cell-Based Workflows

via The Scientist RSS https://ift.tt/3mCfvQS Big discoveries come from miniaturized assays https://ift.tt/eA8V8J August 27, 2021 at 12:46AM

Sparking Drug Discovery Efficiency with CRISPR-Cas9

via The Scientist RSS https://ift.tt/3DhplNX The CRISPR-Cas system, supported by advances in plate reader technology, has transformed drug discovery processes. https://ift.tt/eA8V8J August 27, 2021 at 12:27AM

Study Reveals Declining COVID-19 Vaccine Efficacy Against Infection

via The Scientist RSS https://ift.tt/38f1vUE The vaccines remain protective against serious disease and death. https://ift.tt/eA8V8J August 26, 2021 at 05:00AM

TEST

via The Scientist RSS https://ift.tt/3BfjFlp https://ift.tt/eA8V8J August 26, 2021 at 12:16AM

Genes for Alcohol Use Disorder and Alzheimer’s Risk Overlap: Study

via The Scientist RSS https://ift.tt/3kolPZ9 Genetic, transcriptomic, and epigenetic data reveal molecular mechanisms tying these disorders to each other and to immune disfunction. https://ift.tt/eA8V8J August 25, 2021 at 12:30AM

Studying Cellular Heterogeneity in the Lower Urinary Tract with Spatial Transcriptomics

via The Scientist RSS https://ift.tt/3gtIFNW https://ift.tt/eA8V8J August 24, 2021 at 09:51PM

The Benefits of Electronic Pipettes for RT-PCR

via The Scientist RSS https://ift.tt/3BdxYqZ A fully electronic pipette improves results by reducing variance and user fatigue. https://ift.tt/eA8V8J August 24, 2021 at 07:15PM

FDA Approves Pfizer-BioNTech COVID-19 Vaccine

via The Scientist RSS https://ift.tt/3j9De8x The milestone marks the first fully-approved COVID-19 vaccine in the United States. https://ift.tt/eA8V8J August 24, 2021 at 06:20AM

September 22, 2021 - Winning Westerns Technique Talk: Perfecting Western Blotting

via The Scientist RSS https://ift.tt/3j9tX0g Learn tips and tricks for optimizing Western blot experiments in this workshop. https://ift.tt/eA8V8J August 23, 2021 at 10:07PM

September 21, 2021 - Winning Westerns Technique Talk: Perfecting Western Blotting

via The Scientist RSS https://ift.tt/3ydyWBk Learn tips and tricks for optimizing Western blot experiments in this workshop. https://ift.tt/eA8V8J August 23, 2021 at 09:42PM

Cell Biologist David Sabatini Fired for Sexual Harassment

via The Scientist RSS https://ift.tt/3gkhWDu The researcher, known for his work on the mTOR signaling pathway, is no longer with MIT's Whitehead Institute or HHMI following an investigation into his conduct. https://ift.tt/eA8V8J August 23, 2021 at 01:24AM

Baby Talk: Bat Pups Babble Like Human Infants

via The Scientist RSS https://ift.tt/3j2kTdx By studying the vocal behavior of 20 baby bats from birth to weaning, researchers have identified striking similarities between how young humans and bats develop communication skills. https://ift.tt/eA8V8J August 21, 2021 at 01:23AM

The Baker Company appoints Vice President & Commercial Director, Baker Europe

via The Scientist RSS https://ift.tt/3j1HB5J The Baker Company, Inc. ("Baker") headquartered in Sanford, Maine U.S.A is pleased to announce the appointment of Diko Strietman to Vice President & Commercial Director, Baker Europe. Mr. Strietman will serve as Baker's top commercial executive representing each of the operating companies and associated brands within the EMEA. In this capacity he will guide strategic growth plans as well as provide oversight and direction over the commercial activities and customer facing personnel within Europe and the UK. https://ift.tt/eA8V8J August 21, 2021 at 12:28AM

Fat Cells Send Mitochondrial Distress Signals to the Heart

via The Scientist RSS https://ift.tt/2W9Au2f Vesicles containing fragments of the organelles released from stressed adipocytes protect the heart against oxygen deprivation, a study in mice shows. https://ift.tt/eA8V8J August 20, 2021 at 08:30PM

Neuron-Released Protein Can Set Off Inflammation: Study

via The Scientist RSS https://ift.tt/3AVLEXf Research in mice suggests that moderating nerve activity with drugs or electrical pulses could modify tissue immune responses, curtailing the chronic pain often associated with inflammatory conditions. https://ift.tt/eA8V8J August 20, 2021 at 02:08AM

Snakes on a Plain

via The Scientist RSS https://ift.tt/2W6c7Cn Researchers discover that rattlesnakes change their rattling frequency when a perceived threat approaches--tricking humans into thinking the snake is closer than it really is. https://ift.tt/eA8V8J August 20, 2021 at 12:47AM

Multimode Plate Reader Applications for Microbiology

via The Scientist RSS https://ift.tt/3y2Csi7 Modern plate readers perform a wide range of applications, making them invaluable for microbiome research. https://ift.tt/eA8V8J August 19, 2021 at 08:51PM

Sea Snake “Attacks” Are Cases of Mistaken Identity: Study

via The Scientist RSS https://ift.tt/3szGxJA The Scientist spoke to marine biologist Tim Lynch, who dusted off 25-year-old data from his PhD to figure out why olive sea snakes approach divers so often. He says the animals, especially the males, likely confuse people for fellow snakes. https://ift.tt/eA8V8J August 19, 2021 at 08:30PM

Cellular Biologist Michael Mueckler Dies at 67

via The Scientist RSS https://ift.tt/3xYlnpA His work centered on the mechanisms of glucose transport into cells. https://ift.tt/eA8V8J August 19, 2021 at 02:43AM

Antisense Oligonucleotides Cross Rodents' Blood-Brain Barrier

via The Scientist RSS https://ift.tt/3iZmhh8 RNA-DNA complexes that were modified with cholesterol made it into the brains of rats and mice, where they knocked down target genes. https://ift.tt/eA8V8J August 19, 2021 at 12:30AM

Methylation Sequencing in Cancer Detection

via The Scientist RSS https://ift.tt/3CXjA7N Discover how efforts to uncover the genome's methylation patterns advance cancer detection https://ift.tt/eA8V8J August 18, 2021 at 07:20PM

Building Better Organoids

via The Scientist RSS https://ift.tt/3xUKcCO Explore tissue-specific protocols for growing organoids from primary tissue or stem cells. https://ift.tt/eA8V8J August 18, 2021 at 01:30AM

Spatial Profiling of Immune Signatures in the Tumor Microenvironment

via The Scientist RSS https://ift.tt/3iTNSQQ Explore an in situ transcriptomic approach for mapping target genes in heterogeneous tumor tissues. https://ift.tt/eA8V8J August 18, 2021 at 01:05AM

Sino Biological Announces Successful Closing of 4.98 Billion RMB Public Offering and Listing on the Shenzhen ChiNext Stock Exchange

via The Scientist RSS https://ift.tt/3APC8F7 Sino Biological, Inc. (“Sino Biological” or the “Company”), a biotechnology company which provides biological research reagents and related technical contract research services, announced a successful listing on the Shenzhen Stock Exchange subsidiary ChiNext under the stock abbreviation Sino Biological and stock code 301047. A total of 17 million shares were issued for a total of 4.98 billion RMB raised during this initial public offering. https://ift.tt/eA8V8J August 17, 2021 at 07:29PM

DNA Unlocked - A Special 3-Part Q&A Series

via The Scientist RSS https://ift.tt/3AtvV1o Dive deeper into the DNA Unlocked podcasts https://ift.tt/eA8V8J August 11, 2021 at 10:01PM

Ivory Coast Confirms First Ebola Case Since 1994

via The Scientist RSS https://ift.tt/3yNEzHH Officials say it's not yet clear whether this case is linked to an outbreak in Guinea earlier this summer. https://ift.tt/eA8V8J August 17, 2021 at 01:55AM

Q&A: What You Need to Know About Melioidosis

via The Scientist RSS https://ift.tt/3iPpgsh CDC investigators continue to search for the source of the bacteria that caused four infections—two of them lethal—in four different states. The Scientist spoke with melioidosis expert Bart Currie about the disease. https://ift.tt/eA8V8J August 17, 2021 at 12:47AM

A More Sensitive Way to Determine Protein Structure

via The Scientist RSS https://ift.tt/3skQ3A7 Reliable protein stability and similarity measurements using microfluidic modulation spectroscopy https://ift.tt/eA8V8J August 16, 2021 at 11:28PM

Investigating Genetic and Epigenetic Landscapes with Long-Read Sequencing

via The Scientist RSS https://ift.tt/3AM5kg9 Matthew Naish will discuss what he learned about Arabidopsis thaliana centromeres from long-read sequencing experiments. https://ift.tt/eA8V8J August 14, 2021 at 01:19AM

Engineered Yeast Robots Destroy Inflammatory Molecules in an IBD Mouse Model

via The Scientist RSS https://ift.tt/3m3BCPL Scientists added a gene circuit that senses and neutralizes proinflammatory ATP to yeast, taking another step towards precision medicine. https://ift.tt/eA8V8J August 16, 2021 at 07:47PM

Could a Synthetic Probiotic Replace a Strict Diet for Patients with Phenylketonuria?

via The Scientist RSS https://ift.tt/3xX5fVm Synthetic biologists introduced an engineered microbe that may lead to new treatment options for phenylketonuria. https://ift.tt/eA8V8J August 16, 2021 at 07:23PM

A New COVID-19 Spit Test Is as Easy as 1-2-3

via The Scientist RSS https://ift.tt/2UmAWJL A device smaller than two stacked decks of cards can reliably detect and discriminate between SARS-CoV-2 variants in spit in less than an hour with results that glow. https://ift.tt/eA8V8J August 16, 2021 at 07:08PM

Indigenous Filipino Group Has Highest Known Denisovan Ancestry

via The Scientist RSS https://ift.tt/37IKFNw Researchers found the relatively high proportion of DNA from a hominin cousin—nearly 5 percent—when they scanned more than 1,000 genomes from 118 distinct ethnic groups. https://ift.tt/eA8V8J August 14, 2021 at 02:50AM

Discovered: Fossilized Spores Suggestive of Early Land Plants

via The Scientist RSS https://ift.tt/3jNJToi Spores found in 480 million-year-old rock bring the fossil record in line with molecular estimates of when plants first adapted to life on land. https://ift.tt/eA8V8J August 12, 2021 at 11:30PM

Participant’s Diagnosis Halts Gene Therapy Clinical Trial

via The Scientist RSS https://ift.tt/3yLzOhN The FDA pauses the research program on a lentivirus-based treatment for a rare neurological condition after a patient developed a bone marrow disorder that could presage leukemia. https://ift.tt/eA8V8J August 12, 2021 at 11:19PM

A Self-Contained COVID-19 Test with 3-D Printed Parts

via The Scientist RSS https://ift.tt/2VPk679 The makers of the CRISPR-based testing platform, called miSHERLOCK, say it could enable people at home or physicians in resource-limited environments to detect SARS-CoV-2--and eventually, other pathogens. https://ift.tt/eA8V8J August 12, 2021 at 02:23AM

Aging and Cancer: A Complex Relationship

via The Scientist RSS https://ift.tt/3lV8XfF An expert panel will discuss how aging affects cancer risk, development, and treatment practices. https://ift.tt/eA8V8J August 12, 2021 at 01:08AM

Aubrey de Grey on Leave After Sexual Harassment Allegations

via The Scientist RSS https://ift.tt/3ACCE9d Last night, two women publicly accused the famed anti-aging researcher of inappropriately bringing up sex in the workplace, and they say they are not his only victims. https://ift.tt/eA8V8J August 12, 2021 at 12:30AM

Antibodies Stop Sperm in Their Tracks

via The Scientist RSS https://ift.tt/3CyWbcJ Engineered antibodies trap and immobilize human sperm in the reproductive tract of female sheep, paving the way for possible use as a nonhormonal contraceptive in people. https://ift.tt/eA8V8J August 12, 2021 at 12:13AM

DNA Unlocked - A Special 5-Part Podcast Series

via The Scientist RSS https://ift.tt/3fVjAv1 DNA Unlocked is a special edition podcast series produced by The Scientist’s creative services team. https://ift.tt/eA8V8J August 11, 2021 at 10:22PM

DNA Unlocked - A Special 3-Part Q&A Series

via The Scientist RSS https://ift.tt/3AtvV1o Dive deeper into the DNA Unlocked podcasts https://ift.tt/eA8V8J August 11, 2021 at 10:01PM