Skip to main content

Posts

Showing posts from October, 2021

Labtalk - Hijacking Genes: Uncovering the Cause of Lineage Ambiguous Leukemia

via The Scientist RSS https://ift.tt/3muWyih Chromosomal rearrangements reposition influential and often overlooked non-coding elements in the genome to hijack genes and cause cancer. https://ift.tt/eA8V8J October 28, 2021 at 10:51PM

Spider Uses its Web Like a Giant Engineered Ear

via The Scientist RSS https://ift.tt/2ZLcLHz Bridge spiders "outsource" their hearing by building webs that double as acoustic arrays, allowing them to perceive sounds from great distances. https://ift.tt/eA8V8J October 30, 2021 at 03:22AM

Q and A: Nearly Every Single Human Gene Can Be Linked to Cancer

via The Scientist RSS https://ift.tt/31jzcUZ The Scientist spoke with University of Liverpool aging and longevity researcher Joao Pedro de Magalhaes about how human biases can influence scientific priorities and outcomes in genetics. https://ift.tt/eA8V8J October 30, 2021 at 03:20AM

Harvard Student Strike a Warning to University

via The Scientist RSS https://ift.tt/3brdrnT Graduate students planned a three-day-long strike to demand fair pay, union security, and improved protections against sexual harassment and discrimination. If an agreement isn’t met, the union says they may strike longer, potentially disrupting university research. https://ift.tt/eA8V8J October 30, 2021 at 01:58AM

A Double-Edged Sword: When the Immune System Turns Against Us

via The Scientist RSS https://ift.tt/3vZhIbB Klaus Ley and Neeloffer Mookherjee will explore the relationships between inflammation, autoimmunity, and pathology. https://ift.tt/eA8V8J October 30, 2021 at 01:10AM

Flying Solo: Parthenogenesis Discovered in California Condors

via The Scientist RSS https://ift.tt/3BwiYUG Genetic analyses uncover asexual reproduction by two female California condors despite access to fertile mates. https://ift.tt/eA8V8J October 30, 2021 at 12:21AM

Same RNA Acts in Neurodegeneration and Cancer

via The Scientist RSS https://ift.tt/3pV3aZH The long noncoding RNA MINCR, implicated in ALS and Alzheimer's disease as well as several types of cancer, appears to function differently when present at high versus low levels. https://ift.tt/eA8V8J October 30, 2021 at 12:20AM

Vampire Bats’ Taste for Blood Seen in Lost Genes

via The Scientist RSS https://ift.tt/3GytAGs According to a preprint, the common vampire bat lacks 13 genes present in other bat species, which may help explain their blood-only diet and other curious aspects of their lifestyle. https://ift.tt/eA8V8J October 29, 2021 at 02:55AM

Hope, Concern Surround WHO Green Light of First Malaria Vaccine

via The Scientist RSS https://ift.tt/3nJRvKy RTS,S has several flaws but could still save tens of thousands of lives, experts say. https://ift.tt/eA8V8J October 29, 2021 at 01:38AM

Genome Spotlight: Mandarinfish (Synchiropus splendidus)

via The Scientist RSS https://ift.tt/3jGIPmT The high-quality genome sequence sheds light on the colorful nature of these popular aquarium fish. https://ift.tt/eA8V8J October 28, 2021 at 10:30PM

A Scalable Process to Efficiently Manufacture Adeno-Associated Viral Vectors

via The Scientist RSS https://ift.tt/3EpK7KV An optimized AAV production system allows researchers to consistently generate high virus titers. https://ift.tt/eA8V8J October 28, 2021 at 08:59PM

A Scalable Process to Efficiently Manufacture Adeno-Associated Viral Vectors

via The Scientist RSS https://ift.tt/3vR9rXb https://ift.tt/eA8V8J October 28, 2021 at 08:59PM

Revealing Peer Reviewer Identities Could Introduce Bias: Study

via The Scientist RSS https://ift.tt/3ClC8h7 An analysis finds that reviewers are more likely to choose to be de-anonymized when their reviews are positive, suggesting instituting a fully open process might discourage negative feedback. https://ift.tt/eA8V8J October 28, 2021 at 02:03AM

Harnessing novel technology and a non-profit model to meet the needs patients with ultra-rare diseases

via The Scientist RSS https://ift.tt/3bdu2eR https://ift.tt/eA8V8J October 27, 2021 at 11:17PM

Can Saliva Replace Blood for DNA Collection and Analysis?

via The Scientist RSS https://ift.tt/3CmBss4 Saliva offers a less invasive and more cost-effective alternative for abundant high-quality DNA collection. https://ift.tt/eA8V8J October 27, 2021 at 09:33PM

Paleontologists Find Possible Dinosaur DNA

via The Scientist RSS https://ift.tt/3miXUge A report of preserved fragments of nuclei and chromatin in a fossilized femur of a 125-million-year-old Caudipteryx dinosaur elicits skepticism. https://ift.tt/eA8V8J October 27, 2021 at 01:55AM

Autism-Linked Gene SYNGAP1 Molds Synaptic Plasticity, Learning

via The Scientist RSS https://ift.tt/3vMl3KU The finding may help to explain why people with SYNGAP1 mutations tend to have learning difficulties and a high tolerance for pain. https://ift.tt/eA8V8J October 27, 2021 at 12:46AM

Understanding COVID’s Long Game

via The Scientist RSS https://ift.tt/3nfkvcE Floyd Chilton and Thomas Bumol shine light on the pathways that SARS-CoV-2 hijacks to cause disease. https://ift.tt/eA8V8J October 22, 2021 at 01:18AM

Metabolomic Links Between Environmental Exposures and Human Health

via The Scientist RSS https://ift.tt/3GqNkvk Experts discuss how untargeted metabolomic studies connect environmental factors with human disease. https://ift.tt/eA8V8J October 26, 2021 at 12:33AM

Prosthetic Device Partially Restores Blind Biology Teacher's Vision

via The Scientist RSS https://ift.tt/3GnidB1 With the help of special glasses that interface with electrodes embedded in her brain, Berna Gomez was able to read letters and distinguish shapes for the first time in 16 years. https://ift.tt/eA8V8J October 26, 2021 at 05:55PM

Early Successes Make CRISPR-Based Medicine a Possibility

via The Scientist RSS https://ift.tt/3pzukou CRISPR-Cas9’s molecular scissors—thus far limited to the lab bench—may soon find themselves at work directly in the human body. https://ift.tt/eA8V8J October 25, 2021 at 11:42PM

From Bench to Boardroom

via The Scientist RSS https://ift.tt/3BaursR Taking inspiration from her PhD research, Ana Moreno formed company where scientists use CRISPR to treat chronic pain https://ift.tt/eA8V8J October 25, 2021 at 10:17PM

Thinking Digital: When qPCR Doesn’t Make the Cut

via The Scientist RSS https://ift.tt/3pzAHZh Bio-Rad experts Eddy van Collenburg and Jörg Bantin will discuss where your research can greatly benefit from using ddPCR rather than qPCR, as well as how to ensure a seamless transition to ddPCR. https://ift.tt/eA8V8J October 20, 2021 at 06:21PM

Controlling Western Blot Quality and Compliance

via The Scientist RSS https://ift.tt/3juYIN1 Learn how to follow pharmaceutical industry regulations when performing western blot experiments from start to finish. https://ift.tt/eA8V8J October 22, 2021 at 11:09PM

Charting a Path to Clean Laboratory Air

via The Scientist RSS https://ift.tt/3Ebf0mh https://ift.tt/eA8V8J October 22, 2021 at 11:08PM

Plants Use RNA to Talk to Neighbors

via The Scientist RSS https://ift.tt/3G7eTd7 A study finds that plants sharing the same growth medium can exchange microRNAs that silence genes in the recipient, suggesting the nucleic acids may act as signaling molecules. https://ift.tt/eA8V8J October 22, 2021 at 03:12AM

University of Pittsburgh Faculty Unionize

via The Scientist RSS https://ift.tt/3B3ospP The faculty voted 1511 to 612 to affiliate with United Steelworkers. https://ift.tt/eA8V8J October 22, 2021 at 02:15AM

Stress-Induced Molecular Globs Boost Bacterial Fitness

via The Scientist RSS https://ift.tt/2ZaNCW2 Liquid conglomerations of molecules that form in bacterial cells in response to stress promote the cells’ survival, a study finds. https://ift.tt/eA8V8J October 22, 2021 at 12:37AM

Red Blood Cells Activate Innate Immune System

via The Scientist RSS https://ift.tt/3joenh7 Researchers link the ability of the cells to bind and present DNA from pathogens and cell death to anemia, which is common in COVID-19, and immune activation. https://ift.tt/eA8V8J October 21, 2021 at 05:39AM

Surgeons Successfully Transplant a Pig Kidney into a Person

via The Scientist RSS https://ift.tt/3E4k23X The achievement bolsters hopes that nonhuman animals could be used to remedy the shortage of transplantable organs. https://ift.tt/eA8V8J October 21, 2021 at 02:46AM

Sex of Fetus Affects Immune Response to COVID-19 During Pregnancy

via The Scientist RSS https://ift.tt/2ZdydEX Male placentas produce more proinflammatory molecules than female placentas, while people carrying male fetuses produce fewer antibodies in response to infection, a study finds. https://ift.tt/eA8V8J October 21, 2021 at 12:17AM

High-Quality Screening and Target Validation During Drug Development

via The Scientist RSS https://ift.tt/3G5OYm3 Drew Adams will discuss his work developing therapeutics that promote remyelination for neurological diseases. https://ift.tt/eA8V8J October 18, 2021 at 09:09PM

Famous South African Sardine Run Doesn’t Benefit Sardines: Study

via The Scientist RSS https://ift.tt/3piCxNK An analysis suggests that a commercially important mass migration of fish may have no real adaptive value. https://ift.tt/eA8V8J October 20, 2021 at 01:39AM

Genetic Risks for Depression Differ Between Ancestral Groups

via The Scientist RSS https://ift.tt/3E1UnZL A large genome-wide association study in East Asians uncovers novel genetic links to depression, calling attention to the consequences of underrepresentation of non-European groups in genetic research data. https://ift.tt/eA8V8J October 20, 2021 at 12:50AM

Charting a Path to Clean Laboratory Air

via The Scientist RSS https://ift.tt/3vxICqL Are you working with pathogens or volatiles? Use this flowchart to determine what safety cabinet or fume hood is necessary for any experimental situation. https://ift.tt/eA8V8J October 19, 2021 at 06:01PM

Leading Japanese Primate Research Center is Closing

via The Scientist RSS https://ift.tt/3vsgkOr Kyoto University is shuttering its Primate Research Institute after its director was dismissed for misuse of funding. https://ift.tt/eA8V8J October 19, 2021 at 05:56PM

Mice that Survive Infection Pass on Stronger Immunity

via The Scientist RSS https://ift.tt/3lQVq8j Offspring of animals subjected to a real or simulated pathogen were more able to fend off disease, a study finds. https://ift.tt/eA8V8J October 19, 2021 at 02:06AM

High-Throughput Solutions for Lead Candidate Discovery

via The Scientist RSS https://ift.tt/3vmOiE3 New technologies allow researchers to scale up assays for cellular functions. https://ift.tt/eA8V8J October 18, 2021 at 11:20PM

Scientists Face a Third Round of Charges by Mexican Government

via The Scientist RSS https://ift.tt/3vgwrOU Nearly three dozen of Mexico’s leading researchers are being accused of money laundering, embezzlement, and organized crime, a move other academics say is politically motivated. https://ift.tt/eA8V8J October 16, 2021 at 02:10AM

Dotmatics partners with RockStep Solutions to provide an integrated solution for digitalized in vivo drug discovery

via The Scientist RSS https://ift.tt/3j5CKjz https://ift.tt/eA8V8J October 16, 2021 at 01:16AM

Understanding Cancer Evolution Through the Lens of Single Cell Genomics

via The Scientist RSS https://ift.tt/2YUsFyt Nicholas Navin and Lars Velten discuss sampling, sequencing, and tracing single cells to study how cancer cells adapt to various environments. https://ift.tt/eA8V8J October 15, 2021 at 01:13AM

VectorBuilder and Landau enter into strategic partnership to establish world’s first primate gene therapy R&D center

via The Scientist RSS https://ift.tt/3FQ7JK2 https://ift.tt/eA8V8J October 16, 2021 at 12:58AM

What Research Says About the CDC's New 3-Foot Quarantine Rule

via The Scientist RSS https://ift.tt/3AKD90P The CDC now suggests that only children who were within 3 feet, not 6 feet, of an infected student should quarantine, provided they were masked in a classroom. Does the science support this change? https://ift.tt/eA8V8J October 15, 2021 at 10:19PM

Undruggable - A Special 5-Part Podcast Series

via The Scientist RSS https://ift.tt/3j5BHA7 Welcome to Undruggable, a special edition podcast series produced by The Scientist’s Creative Services Team. https://ift.tt/eA8V8J October 12, 2021 at 11:49PM

Improving Reproducibility with Automated Liquid Handling

via The Scientist RSS https://ift.tt/3p8Iehr Automated liquid handling reduces manual labor and improves precision, reproducibility, and throughput. https://ift.tt/eA8V8J October 14, 2021 at 09:35PM

How Commensal Gut Bacteria Keep Pathogens in Check

via The Scientist RSS https://ift.tt/3iZQ9JQ Recent studies describe how resident microbiota appear to outcompete unwelcome visitors, either with superior weaponry or by guzzling up local resources.   https://ift.tt/eA8V8J October 14, 2021 at 07:30PM

Sound Waves Aid Brain Tumor Treatment

via The Scientist RSS https://ift.tt/3FJgA01 In a small clinical study, focusing ultrasound beams on tumors in patients’ brains helped open the blood-brain barrier to facilitate drug delivery. https://ift.tt/eA8V8J October 14, 2021 at 01:30AM

Scientists Use Photosynthesis to Power an Animal’s Brain

via The Scientist RSS https://ift.tt/2YJrHW3 Injecting oxygen-generating algae into tadpoles allows brain activity to continue in the absence of oxygen, researchers find. https://ift.tt/eA8V8J October 14, 2021 at 12:36AM

Repurposed Drug Reverses Signs of Alzheimer's in Mice, Human Cells

via The Scientist RSS https://ift.tt/3iY5o6e Researchers say they hope to launch a clinical trial to test bumetanide, a diuretic approved in 2002, but how it might improve neural functioning is unclear. https://ift.tt/eA8V8J October 13, 2021 at 01:30AM

Neuroscientist Mortimer Mishkin Dies at 94

via The Scientist RSS https://ift.tt/3FAksRb His work bridged the gap between psychology and neurobiology. https://ift.tt/eA8V8J October 07, 2021 at 01:38AM