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Showing posts from November, 2021

Cancer Cell Nanotubes Hijack Mitochondria from Immune Sentinels

via The Scientist RSS https://ift.tt/3d1WjWH The mitochondria stolen via these tiny connections give tumor cells a metabolic boost while the T cells are left weakened, according to in vitro experiments. https://ift.tt/eA8V8J November 30, 2021 at 09:10PM

2,000-Year-Old Salmon DNA Reveals Secret to Sustainable Fisheries

via The Scientist RSS https://ift.tt/3d2tnxK Genomic analysis of ancient chum salmon bones and cultural knowledge from the Tsleil-Waututh Nation suggest that people in the Pacific Northwest managed fisheries for thousands of years by harvesting males and releasing females. https://ift.tt/eA8V8J November 30, 2021 at 01:52AM

LabTalk Podcast - Phagocidal Macrophages: A New Battle Tactic Against Resistant Cancers

via The Scientist RSS https://ift.tt/3riNlwh The adaptive and innate immune responses collaborate to attack T-cell resistant cancer cells. https://ift.tt/eA8V8J November 23, 2021 at 07:04PM

Simplifying PCR set-up with INTEGRA's range of pipettes

via The Scientist RSS https://ift.tt/3p0hLAP INTEGRA Biosciences’ selection of liquid handling tools provides scientists worldwide with the solutions they need for their PCR workflows. https://ift.tt/eA8V8J November 25, 2021 at 05:32PM

Over the Counter Antihistamines Could Help Against Cancer

via The Scientist RSS https://ift.tt/3oWGHZR The binding of histamine with one of its receptors within the tumor environment makes cancer cells more resistant to immunotherapy, according to a new study. Blocking that binding could improve responses to treatment. https://ift.tt/eA8V8J November 25, 2021 at 03:30AM

Improving Cancer Diagnostics with Circulating Tumor Cells in Blood

via The Scientist RSS https://ift.tt/3CJ7mOM Liquid biopsies: A new era in blood-based cancer detection methods https://ift.tt/eA8V8J November 25, 2021 at 01:51AM

Johnson & Johnson Vaccine Garners First Full Approval

via The Scientist RSS https://ift.tt/3cIIv30 Health Canada has given the single COVID-19 shot the official greenlight for use in people 18 and older. https://ift.tt/eA8V8J November 24, 2021 at 11:30PM

Genome Spotlight: California Sea Gooseberry (Hormiphora californensis)

via The Scientist RSS https://ift.tt/30T3vC2 The first chromosome-level genome assembly for a ctenophore may allow scientists to finally resolve the roots of the animal family tree. https://ift.tt/eA8V8J November 24, 2021 at 10:30PM

Walter Gratzer, Biophysical Chemist and Science Writer, Dies at 89

via The Scientist RSS https://ift.tt/3FEviEX His career bridged impactful research in molecular biology and biochemistry with prolific science writing for academic and nonacademic audiences alike. https://ift.tt/eA8V8J November 24, 2021 at 03:22AM

Q&A: Potential Partiality in Scientific Publishing

via The Scientist RSS https://ift.tt/3xhDyYj The Scientist interviewed clinical pharmacologist Clara Locher, coauthor of a new survey aimed at detecting editorial bias, regarding her team’s findings about biomedical publishing. https://ift.tt/eA8V8J November 24, 2021 at 02:57AM

CDC Pathology Investigator Dies Unexpectedly at 65

via The Scientist RSS https://ift.tt/30Ul7gI Sherif Zaki worked at the Centers for Disease Control and Prevention for more than 30 years, and was renowned for uncovering crucial intel on various outbreak-causing scourges, from Ebola and Zika to SARS and influenza. https://ift.tt/eA8V8J November 24, 2021 at 01:35AM

Q&A: How to Keep Antarctica Safe from Invasive Species

via The Scientist RSS https://ift.tt/3nK4vkn The Scientist spoke with University of Wollongong ecologist Dana Bergstrom about protecting the continent's native plants and animals in the face of climate change and a growing human presence. https://ift.tt/eA8V8J November 24, 2021 at 12:30AM

HHMI Kickstarts $2 Billion Initiative to Boost Diversity in STEM

via The Scientist RSS https://ift.tt/3CF7ChO The Howard Hughes Medical Institute will invest the funds over 10 years across all stages of the STEM pipeline. https://ift.tt/eA8V8J November 23, 2021 at 11:50PM

LevitasBio Announces New Integrated Approaches to Sample Preparation and Cell Enrichment

via The Scientist RSS https://ift.tt/3CIhmrp LevitasBio has announced the expansion of its product portfolio with the release of two new product lines that will enable researchers and laboratory personnel to better process and characterize human, animal and plant samples. https://ift.tt/eA8V8J November 23, 2021 at 07:41PM

Reducing cell culture contamination with INTEGRA's versatile pipettes

via The Scientist RSS https://ift.tt/3r1HBXK INTEGRA Biosciences – a leading provider of high quality laboratory equipment – supplies a comprehensive range of liquid handling tools that are ideal for sterile cell biology workflows. https://ift.tt/eA8V8J November 23, 2021 at 07:21PM

Bio-Rad Introduces StarBright UltraViolet 400 Dye for Flow Cytometry

via The Scientist RSS https://ift.tt/32ti3Zt StarBright UltraViolet 400 Dye Offers Maximal Brightness and Narrow Excitation and Emission Profiles for Precise Resolution https://ift.tt/eA8V8J November 23, 2021 at 07:09PM

Exposure to Chemical from Babies Linked to Aggression

via The Scientist RSS https://ift.tt/3cIwRoE A study finds that the odorless compound hexadecanal, or HEX, increases aggressive behavior in women but has a calming effect on men. https://ift.tt/eA8V8J November 23, 2021 at 03:55AM

Cell Diversity Could Spell Trouble for Animal Models of Cancer

via The Scientist RSS https://ift.tt/3nztXch Tracking human cancers in mice shows some unexpected cell changes that could undermine translational research.   https://ift.tt/eA8V8J November 20, 2021 at 02:32AM

Study Links Flu to Increased Parkinson's Risk a Decade Later

via The Scientist RSS https://ift.tt/3cvd24h Epidemiological research suggests that a flu diagnosis might be one factor in the eventual onset of the neurodegenerative disease, but experts say it doesn't prove a causal relationship. https://ift.tt/eA8V8J November 20, 2021 at 02:30AM

Gut Infections Help Shield Intestinal Neurons from Future Damage

via The Scientist RSS https://ift.tt/3nz0aQZ In mice, a kind of immune memory appears to protect the cells against future harm, a finding that could provide insight into treatments for irritable bowel syndrome and other inflammatory digestive conditions. https://ift.tt/eA8V8J November 19, 2021 at 11:19PM

Underlying Pathways: The Key to Progress in Rheumatology?

via The Scientist RSS https://ift.tt/3nu3sVE Understanding immune pathways and disease mechanisms helps address the unmet needs of patients living with difficult-to-treat rheumatic diseases. https://ift.tt/eA8V8J November 17, 2021 at 10:06PM

Scientists Step Closer to Vaccine for Tick Bites

via The Scientist RSS https://ift.tt/3qPXpNl NIH researcher Andaleeb Sajid discusses her study’s finding that ticks were unable to feed on vaccinated guinea pigs, preventing transmission of the pathogen that causes Lyme disease. https://ift.tt/eA8V8J November 19, 2021 at 01:45AM

DNA Damage Makes Zebrafish Sleepy

via The Scientist RSS https://ift.tt/3CyK4em Buildup of a DNA-repair protein in brain cells spurs shut-eye in the fish, a study finds, and similar results in mice suggest the mechanism is widespread in animals. https://ift.tt/eA8V8J November 18, 2021 at 10:11PM

Finding CAR T Cells in Solid Tumors at Cell-Level Resolution

via The Scientist RSS https://ift.tt/3Fspe23 Rita Pfeifer will discuss visualizing and quantifying CAR T-cell infiltration into solid tumors with 3-D light sheet fluorescence microscopy (LSFM). https://ift.tt/eA8V8J November 13, 2021 at 12:26AM

Woman’s Body Appears to Rid Itself of HIV

via The Scientist RSS https://ift.tt/3qQRYxw Researchers report what appears to be the second case of a person’s immune system clearing the virus on its own. https://ift.tt/eA8V8J November 18, 2021 at 07:05PM

Improving ELISA-Based Host Cell Protein Detection for Biologic Production

via The Scientist RSS https://ift.tt/3CujD9A Discover methods to improve coverage analysis of any cell line. https://ift.tt/eA8V8J November 18, 2021 at 01:43AM

Lungfish Cocoons Are Alive, Sort Of

via The Scientist RSS https://ift.tt/3oG9vFQ Researchers find that the protective outer layer that lungfish make to survive extended dry periods--once thought to be a simple mucus shell--contains immune cells that trap bacteria and protect the animals from infection. https://ift.tt/eA8V8J November 18, 2021 at 12:30AM

The Scientist Speaks - Molecular Farming: The Future of Pharmaceuticals

via The Scientist RSS https://ift.tt/3HvezFN Julian Ma discusses past, present, and future uses of plant biotechnology for disease treatments. https://ift.tt/eA8V8J November 16, 2021 at 09:02PM

Tool Identifies Likely Reservoir Species for SARS-CoV-2

via The Scientist RSS https://ift.tt/3chfDP8 Researchers used sequencing data and phenotypic traits to predict which of 5,400 species were most likely to be susceptible to contracting and spreading the virus back to humans. https://ift.tt/eA8V8J November 17, 2021 at 05:31AM

Connecting the Transcriptome to the Functional Proteome of Single Cells Using a Novel Platform

via The Scientist RSS https://ift.tt/30FvLYq Rui Zheng and Patrick Paczkowski will discuss a new, highly multiplexed, simultaneous single cell transcriptomics and functional proteomics platform. https://ift.tt/eA8V8J November 11, 2021 at 02:24AM

Biomarkers on the Brain: From Sequencing to Functional Imaging

via The Scientist RSS https://ift.tt/30xpYUM An expert panel will discuss biomarker development for brain disorders and considerations for their clinical use. https://ift.tt/eA8V8J November 16, 2021 at 07:57PM

The Scientist Speaks - Molecular Farming: The Future of Pharmaceuticals

via The Scientist RSS https://ift.tt/3nkhskA https://ift.tt/eA8V8J November 16, 2021 at 09:02PM

Biomarkers on the Brain: From Sequencing to Functional Imaging

via The Scientist RSS https://ift.tt/3qGY2IR https://ift.tt/eA8V8J November 16, 2021 at 07:57PM

Harnessing the Power of Gene Editing for Protein Engineering

via The Scientist RSS https://ift.tt/3owzyPN Targeted, genome-wide CRISPR editing in yeast improves protein yield. https://ift.tt/eA8V8J November 16, 2021 at 02:04AM

Harnessing the Power of Gene Editing for Protein Engineering

via The Scientist RSS https://ift.tt/3Fg59Ms https://ift.tt/eA8V8J November 16, 2021 at 02:04AM

Early Disease Detection with Lateral Flow-Based Immunodiagnostic Tests

via The Scientist RSS https://ift.tt/3kFOnP0 Improve lateral flow-based immunoassays to detect pathogens and biomarkers more accurately. https://ift.tt/eA8V8J November 16, 2021 at 01:58AM

Monitoring Cancer Immune Cell Therapies

via The Scientist RSS https://ift.tt/3kEwIag Single cell and spatial analyses of cell-based cancer therapeutics and patient responses enhance treatment efficacy. https://ift.tt/eA8V8J November 15, 2021 at 10:46PM

Male Snakes Cannibalizing Females Present Evolutionary Puzzle

via The Scientist RSS https://ift.tt/3FhmdBQ The Scientist speaks with organismal biologist Xavier Glaudas about possible reasons for his recent finding that male Montpellier snakes cannibalize female conspecifics. https://ift.tt/eA8V8J November 15, 2021 at 07:32PM

Biden Picks Robert Califf to Head the FDA for a Second Time

via The Scientist RSS https://ift.tt/3HhxVhx The cardiologist was briefly the FDA Commissioner in the Obama Administration, and now has a second chance to act on plans he tried to implement during his first tenure. https://ift.tt/eA8V8J November 13, 2021 at 02:52AM

Training Immune Cells to Be Cancer Killers

via The Scientist RSS https://ift.tt/3ksMghi A career-altering experience as a cancer patient motivated one researcher to design more potent immunotherapies. https://ift.tt/eA8V8J November 13, 2021 at 01:41AM

Can mRNA Vaccine Momentum Propel Tumor Immunotherapies?

via The Scientist RSS https://ift.tt/3Cfz9pM A guide to mRNA-based cancer vaccines and where they’re headed next https://ift.tt/eA8V8J November 13, 2021 at 01:28AM

Webless Jumping Spiders Spin Super Strong Silk

via The Scientist RSS https://ift.tt/3F2DPRM The silk draglines made by zebra jumping spiders are tougher than the silk webbing of orb weaver spiders, even though they’re made at 25 to 35 times the speed. https://ift.tt/eA8V8J November 13, 2021 at 01:53AM

INTEGRA’s VOYAGER helps HIV researchers get more results in significantly less time

via The Scientist RSS https://ift.tt/3C1Cwk4 https://ift.tt/eA8V8J November 12, 2021 at 12:37AM

Bio-Rad Launches Its CFX Opus Dx Real-Time PCR Detection Systems for In Vitro Diagnostics  

via The Scientist RSS https://ift.tt/3F5MHGe The CFX Opus 96 Dx System and the CFX Opus 384 Dx Real-Time PCR Systems Offer Accurate and Precise Quantification to Improve IVD Assay Development and Diagnostic Testing https://ift.tt/eA8V8J November 12, 2021 at 12:07AM

Diet Implicated in Autism-Microbiome Link

via The Scientist RSS https://ift.tt/3F8SfzG The unbalanced gut flora present in some people with autism is not a driver of the condition but rather a consequence of eating behaviors characteristic of the condition, a new study claims. https://ift.tt/eA8V8J November 11, 2021 at 11:30PM

Deep Sea Microbes Produce Graphite-like Carbon

via The Scientist RSS https://ift.tt/30keILu The first evidence of biologically produced elemental carbon inspires more questions than answers. https://ift.tt/eA8V8J November 11, 2021 at 10:43PM

Public Health Pioneer Peter Pharoah Dies at 87

via The Scientist RSS https://ift.tt/3cis4dL Pharoah’s work ended endemic cretinism in a remote region of Papua New Guinea and contributed to the understanding of myriad other perinatal health conditions. https://ift.tt/eA8V8J November 11, 2021 at 08:30PM

Opinion: In Defense of Preprints

via The Scientist RSS https://ift.tt/3F4y4Tu In response to two November 2021 articles in The Scientist that called out preprints as a source of medical misinformation, the cofounders of bioRxiv and medRxiv say it's not the publishing model that's at fault. https://ift.tt/eA8V8J November 11, 2021 at 06:46PM

Neurons Firing Together Generate Spontaneous Pain

via The Scientist RSS https://ift.tt/3bZNVpX Abnormal sympathetic neuron growth leads to simultaneous activation of clusters of sensory neurons, causing the difficult-to-treat sensation. https://ift.tt/eA8V8J November 11, 2021 at 02:40AM

Is COVID-19 Seasonal?

via The Scientist RSS https://ift.tt/3C5xxyX While the weather isn't currently the dominant factor driving SARS-CoV-2 transmission, experts say that in the future COVID-19 may become a disease of winter. https://ift.tt/eA8V8J November 11, 2021 at 01:05AM