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Showing posts from December, 2021

Sino Biological Deposits Recombinant Omicron Proteins and Antibodies to BEI Resources

via The Scientist RSS https://ift.tt/3pHE003 Sino Biological, Inc. (SZSE: 301047) has recently deposited reagents for the Omicron variant, including recombinant proteins to Spike and Nucleocapsid, and antibody products to BEI Resources, a central repository for reagents to support infectious disease research. https://ift.tt/eA8V8J December 31, 2021 at 09:31PM

Scratchy Scalps Help Glue Together Pieces of an Ancient Past

via The Scientist RSS https://ift.tt/3zhLom0 Scientists find human DNA preserved in lice cement from the heads of South American mummies. https://ift.tt/eA8V8J December 30, 2021 at 03:25AM

Ophthamologist Alan Scott Dies at Age 89

via The Scientist RSS https://ift.tt/3sJzTTa The Smith-Kettlewell Eye Research Institute scientist developed Botox for medicinal use. https://ift.tt/eA8V8J December 30, 2021 at 02:30AM

Our Favorite Neuroscience Stories of 2021

via The Scientist RSS https://ift.tt/3qBPjpA From a Nobel prize and photosynthesis-powered brains to neurodegeneration research and controversy over a new Alzheimer’s drug, a look back at some of the biggest brain-related developments of the year. https://ift.tt/eA8V8J December 30, 2021 at 01:59AM

Increasing Chromatography Sensitivity with Ultrapure Water

via The Scientist RSS https://ift.tt/3FFgw0W HPLC-grade water does not adequately separate trace compounds in chromatography experiments. https://ift.tt/eA8V8J December 29, 2021 at 07:18PM

Organoids: Stepping Up from Cells to Organs

via The Scientist RSS https://ift.tt/3evX0Im Discover how important organoids have become to disease research and drug discovery. https://ift.tt/eA8V8J December 29, 2021 at 07:15PM

Streamline Quality Control Workflows to Produce Safe Drugs

via The Scientist RSS https://ift.tt/32Foclk Researchers incorporate an alternative to ELISA and HPLC to characterize lead molecules more efficiently. https://ift.tt/eA8V8J December 29, 2021 at 07:12PM

The Scientist Editors' Favorite Stories of 2021

via The Scientist RSS https://ift.tt/32JQRpa A look back at some of the articles we most enjoyed reading, writing, and editing this year https://ift.tt/eA8V8J December 28, 2021 at 11:10PM

Pandemic Amplifies Postdoc Struggles

via The Scientist RSS https://ift.tt/3FAbbI9 Postdoctoral fellows faced challenges before COVID-19 changed the way academia functions, and these early career scientists report that things have only gotten harder. https://ift.tt/eA8V8J December 28, 2021 at 10:30PM

EO Wilson, Renowned Ant Researcher, Dies at 92

via The Scientist RSS https://ift.tt/3pt7miy The naturalist was recognized for his work on social behavior and pheromones in ants and as a champion of wildlife conservation. https://ift.tt/eA8V8J December 28, 2021 at 01:50AM

The Past, Present, and Future of Cell and Gene Therapy

via The Scientist RSS https://ift.tt/3mq63Pq Embark on the journey of cell and gene therapy—from its conception and development, to its present state, and into its future. https://ift.tt/eA8V8J December 23, 2021 at 11:19PM

A Guide to Comprehensive Epigenetic Analysis

via The Scientist RSS https://ift.tt/3JgD4r2 Technological advances help scientists detect genome-wide DNA methylation and hydroxymethylation levels in parallel. https://ift.tt/eA8V8J December 23, 2021 at 11:11PM

INTEGRA supports groundbreaking brain tumor research

via The Scientist RSS https://ift.tt/3eA4p9P INTEGRA Biosciences is proud to be supporting vital translational research into diffuse intrinsic ponsglioma (DIPG) – a rare childhood brain tumor – at the Ludwig Maximilian University of Munich (LMU) with a festive donation of 20,000 EUR. Brain tumors in children are thankfully rare, but are often associated with poor prognoses and low survival rates. https://ift.tt/eA8V8J December 23, 2021 at 08:41PM

Genome Spotlight: Common Reed (Phragmites australis)

via The Scientist RSS https://ift.tt/3mtYAPf The first reference-quality genome for this grass species could aid managers in understanding and eradicating this highly invasive plant. https://ift.tt/eA8V8J December 23, 2021 at 07:45PM

FDA Authorizes Pfizer's Paxlovid, First Oral Therapy for COVID-19

via The Scientist RSS https://ift.tt/3GYJCsy Given within three days of symptom onset, the pill combination was nearly 90 percent effective at preventing high-risk patients from developing severe illness in a clinical study. https://ift.tt/eA8V8J December 23, 2021 at 07:30PM

Our Favorite Genetics Stories of 2021

via The Scientist RSS https://ift.tt/3msM9n7 Studies The Scientist covered this year illustrate the expanding importance of genetic and genomic research in all aspects of life science, from ecology to medicine. https://ift.tt/eA8V8J December 23, 2021 at 07:00PM

Harvard Chemist Found Guilty of Lying About Chinese Funding

via The Scientist RSS https://ift.tt/3ekE5Ah In a win for the US Department of Justice’s China Initiative, Charles Lieber was convicted for hiding his financial ties to China from federal agencies. https://ift.tt/eA8V8J December 23, 2021 at 03:43AM

Pioneering Sleep Researcher Allan Rechtschaffen Dies at 93

via The Scientist RSS https://ift.tt/3EnEQ5Y Rechtschaffen sought to understand the evolutionary purpose of shut-eye. https://ift.tt/eA8V8J December 23, 2021 at 01:58AM

Quick and Reliable Plant DNA Extraction

via The Scientist RSS https://ift.tt/3sqoBTv An innovative, environmentally-friendly spin kit maximizes DNA isolation. https://ift.tt/eA8V8J December 22, 2021 at 09:29PM

How Cancer Circumvents the Immune System

via The Scientist RSS https://ift.tt/3ErjNji Dario Vignali and Peter Westcott will explore the importance of understanding immune-cancer mechanistic interactions for developing therapeutic approaches. https://ift.tt/eA8V8J December 16, 2021 at 12:04AM

Convalescent Plasma for COVID-19 Cuts Hospitalizations: Preprint

via The Scientist RSS https://ift.tt/33IuX6h Unlike studies of antibody-rich transfusions in hospitalized patients, which overall have not found clear benefits, a new randomized trial finds that early convalescent plasma treatment cuts hospitalizations in half. https://ift.tt/eA8V8J December 22, 2021 at 03:37AM

The Top Retractions of 2021

via The Scientist RSS https://ift.tt/3EjQHST From Star Trek to ivermectin, we look back on some of the most notable about-faces in publishing this year. https://ift.tt/eA8V8J December 22, 2021 at 02:30AM

Technique Talk: Single-Cell Sequencing Experimental Design

via The Scientist RSS https://ift.tt/3qnm3Dc Learn how to balance sample limitations and experimental methods for optimal single-cell sequencing results. https://ift.tt/eA8V8J December 22, 2021 at 02:06AM

Aging in Mice Linked to Misexpression of Class of Genes

via The Scientist RSS https://ift.tt/3qiUyKI Genes lacking a particular structure known as CpG islands tend to go haywire in older cells, a study finds, potentially contributing to key facets of aging. But it's not yet clear if the relationship is causal. https://ift.tt/eA8V8J December 21, 2021 at 09:20PM

Revolutionary Crystallographer Ned Seeman Dies at 75

via The Scientist RSS https://ift.tt/3snqaBu Seeman is best known for establishing the field of DNA nanotechnology. https://ift.tt/eA8V8J December 21, 2021 at 03:40AM

Omicron Propagates 70 Times Faster than Delta in Bronchi: Study

via The Scientist RSS https://ift.tt/3H9uE39 A preprint reports that the new SARS-CoV-2 variant multiplies faster in human bronchial tissue but slower in lung tissue than the Delta variant, potentially explaining how it’s spreading from person to person so quickly. https://ift.tt/eA8V8J December 18, 2021 at 03:49AM

Modeling the Complexity of Human Tumors in 3-D Cell Cultures

via The Scientist RSS https://ift.tt/3yA6HyR In this workshop, learn how to make precision medicine a reality by modeling human cancers in 3-D organoid cultures for drug screening. https://ift.tt/eA8V8J December 18, 2021 at 01:53AM

Modeling the Complexity of Human Tumors in 3-D Cell Cultures

via The Scientist RSS https://ift.tt/3p5X5bL https://ift.tt/eA8V8J December 18, 2021 at 01:53AM

MRC Lead Apologizes Following Bullying Allegations

via The Scientist RSS https://ift.tt/3sfTiL5 In a statement issued by UK Research and Innovation, stem cell biologist Fiona Watt said she was devastated to learn of the impact her actions and behavior on colleagues. https://ift.tt/eA8V8J December 18, 2021 at 12:30AM

Q&A: Fluorescence Lets Diatoms Communicate, Coordinate Behavior

via The Scientist RSS https://ift.tt/3p0cMBd The Scientist spoke with physicist and microbial ecologist Idan Tuval, whose recent paper challenges the assumption that these single-celled organisms only communicate via chemical signals. https://ift.tt/eA8V8J December 17, 2021 at 03:20AM

Some Mammals May Use Specialized Hairs to Detect Predators' Heat

via The Scientist RSS https://ift.tt/3EYUoOO When observed under a microscope, guard hairs from mice resemble optical sensors used in thermal cameras to detect heat, according to a new study. https://ift.tt/eA8V8J December 17, 2021 at 01:59AM

What We Learned About COVID-19 in 2021

via The Scientist RSS https://ift.tt/3yvcp4S As Omicron induces a sense of deja vu at the close of the year, we look back at a few key ways in which our understanding has moved forward. https://ift.tt/eA8V8J December 16, 2021 at 10:03PM

The Common Mouth Microbe That Keeps Popping Up in Tumors

via The Scientist RSS https://ift.tt/3E0zr4C Lab studies link the oral bacteria Fusobacterium nucleatum to cancers from the gut to the head and neck. Could targeting the microbe tackle tumors? https://ift.tt/eA8V8J December 16, 2021 at 12:18AM

Hydrogen Fueled Life’s Origins: Study

via The Scientist RSS https://ift.tt/3oXCOFf A thermodynamic analysis of more than 400 chemical reactions that likely took place in the ancestor of all life finds most would spontaneously occur at hydrothermal vents, thanks to the hydrogen these geological formations emit. https://ift.tt/eA8V8J December 15, 2021 at 08:55PM

The Scientist Speaks - Lipids Predict a Slippery Path Towards Parkinson’s Disease

via The Scientist RSS https://ift.tt/3yw73pT Melissa Vos discusses how lipids’ good intentions become harmful in Parkinson’s Disease. https://ift.tt/eA8V8J December 15, 2021 at 01:20AM

Omicron Appears to Evade Vaccines Better Than Other Variants

via The Scientist RSS https://ift.tt/3m41Oc6 Preliminary studies suggest that existing vaccines falter in preventing symptomatic infections caused by the new coronavirus variant, but protection against severe disease is still high. https://ift.tt/eA8V8J December 15, 2021 at 02:00AM

How Hydras Regenerate Decapitated Heads

via The Scientist RSS https://ift.tt/3m5PPee Hydra vulgaris constantly replenish the cells in their heads and grow new ones to reproduce asexually. But gene expression analyses reveal that regenerating a head after an injury is a very different process. https://ift.tt/eA8V8J December 15, 2021 at 01:15AM

The Next Generation of Immunoassays Support COVID-19 Research

via The Scientist RSS https://ift.tt/3ys7SQw An automated, microfluidic immunoassay system enables researchers to quickly and reliably measure cytokines in patient blood samples. https://ift.tt/eA8V8J December 14, 2021 at 10:52PM

Combinatorial Single Cell CRISPR Screens: Challenges and Applications

via The Scientist RSS https://ift.tt/3oIxwxh An expert panel will discuss how single cell sequencing enhances throughput in CRISPR gene editing applications. https://ift.tt/eA8V8J December 10, 2021 at 11:07PM

Sea Otters Demonstrate that There Is More to Muscle than Just Movement--It Can Also Bring the Heat

via The Scientist RSS https://ift.tt/3s0zRWz Sea otters are born with a supercharged metabolism that helps them stay warm in chilly waters. https://ift.tt/eA8V8J December 14, 2021 at 02:49AM

INTEGRA's guidance to ensure pipette longevity and accuracy

via The Scientist RSS https://ift.tt/3lZnWEr INTEGRA Biosciences – a leading supplier of liquid handling tools – has released comprehensive guidance on how to best care for pipettes to ensure they deliver continuous and prolonged accuracy. https://ift.tt/eA8V8J December 12, 2021 at 11:33PM

Yokogawa Develops Single Cellome System SS2000 for Subcellular Sampling

via The Scientist RSS https://ift.tt/3ymiosx A single-cell analysis solution that revolutionizes efficiency in drug discovery research by automating the collection of specific cells and intracellular components   https://ift.tt/eA8V8J December 12, 2021 at 11:28PM

Car-Sized, Meat-Eating Dinosaur Could Run Faster Than Usain Bolt

via The Scientist RSS https://ift.tt/3s1f6Kt A new analysis of fossil footprints suggests that the 2-meter-tall, 4- to 5-meter-long carnivores that left them could run nearly 45 kilometers per hour, bolstering the evidence that at least some dinosaurs were speedy, agile hunters. https://ift.tt/eA8V8J December 11, 2021 at 03:35AM

Book Club Discussion of Venomous by Christie Wilcox

via The Scientist RSS https://ift.tt/3EKGcsP The Scientist Social Club sat down with the author. https://ift.tt/eA8V8J December 11, 2021 at 03:17AM

Lawrence Tabak Tapped to Serve as Interim NIH Head

via The Scientist RSS https://ift.tt/3rVGRUo The glycoprotein researcher and longtime principal deputy director of the National Institutes of Health will take over from Francis Collins on December 20. https://ift.tt/eA8V8J December 11, 2021 at 02:40AM

An Optimized Culture Medium for Induced Pluripotent Stem Cells

via The Scientist RSS https://ift.tt/31TUAAp An animal component-free culture medium provides a safe and robust alternative for maintaining induced pluripotent stem cells. https://ift.tt/eA8V8J December 11, 2021 at 02:01AM

An Engineer’s Perspective on Autoimmunity

via The Scientist RSS https://ift.tt/3DKHzGg Erika Moore builds biomaterials to study disparate lupus outcomes. https://ift.tt/eA8V8J December 11, 2021 at 01:07AM

Helping the Immune System Keep its Cool

via The Scientist RSS https://ift.tt/3IApC17 Researchers found that lowering the temperature alleviates autoimmunity in mice. https://ift.tt/eA8V8J December 11, 2021 at 12:54AM

Combinatorial Single Cell CRISPR Screens: Challenges and Applications

via The Scientist RSS https://ift.tt/3ENIB62 https://ift.tt/eA8V8J December 10, 2021 at 10:39PM

Retrotransposon RNA Triggers NLRC4 Inflammasome Formation: Study

via The Scientist RSS https://ift.tt/3GAweKK Researchers identify a sensor that sets off inflammation in the absence of infection when it detects RNA from the mobile genetic elements. https://ift.tt/eA8V8J December 10, 2021 at 07:23PM