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Showing posts from March, 2022

A How-to Guide for Planning Single Cell Gene Expression Studies

via The Scientist RSS https://ift.tt/w6qp8SL Follow the roadmap to successful single cell transcriptomic workflows and outputs. https://ift.tt/lKhV5AN March 31, 2022 at 09:41PM

A How-to Guide for Planning Single Cell Gene Expression Studies

via The Scientist RSS https://ift.tt/M7jG3de https://ift.tt/lKhV5AN March 31, 2022 at 09:41PM

The Scientist Speaks - Preventing the Next Pandemic with Organ Chips

via The Scientist RSS https://ift.tt/4tnKDmp Don Ingber discusses how organ-on-a-chip technology helps identify, study, and combat viral variants that could cause the next pandemic. https://ift.tt/lKhV5AN March 30, 2022 at 08:34PM

Arctic Greening Won’t Save the Climate—Here’s Why

via The Scientist RSS https://ift.tt/tQShpr5 The growing season on the tundra is starting earlier as the planet warms, but the plants aren’t sequestering more carbon, a new study finds. https://ift.tt/yIjGWN6 March 30, 2022 at 11:30PM

Are Your Cell Lines What You Think They Are?

via The Scientist RSS https://ift.tt/qniBsMe Learn how to identify contamination and authenticate your cell lines. https://ift.tt/uEJhCoO March 30, 2022 at 12:25AM

Why Might Cells Die or Fail to Thrive in Culture?

via The Scientist RSS https://ift.tt/gT5Nt98 Learn more about cell culture best practices. https://ift.tt/uEJhCoO March 30, 2022 at 12:14AM

Monitoring and Controlling Water Quality for Drug Development

via The Scientist RSS https://ift.tt/Ji0UYHI A detailed look at ensuring water quality compliance for pharmaceutical applications https://ift.tt/uEJhCoO March 29, 2022 at 11:42PM

Unmasking the Complex Biology of Multiple Sclerosis

via The Scientist RSS https://ift.tt/8UTgLpq Single cell technology reveals novel mechanisms of MS pathogenesis. https://ift.tt/uEJhCoO March 29, 2022 at 11:33PM

Metformin Prescriptions Linked to Sons’ Birth Defects

via The Scientist RSS https://ift.tt/NEPvrk6 A new cohort study finds that boys whose fathers took the type 2 diabetes drug metformin three months before their conception were more likely to have a birth defect. https://ift.tt/uEJhCoO March 29, 2022 at 11:06PM

Soil Microbes Sacrifice Ribosomes in Response to Warming

via The Scientist RSS https://ift.tt/WuMBy9b When soil heats up, microbes scale back protein synthesis machinery by making use of higher reaction rates that occur at higher temperatures, a study finds. https://ift.tt/uEJhCoO March 29, 2022 at 10:59PM

The Many Facets of T Cell Exhaustion

via The Scientist RSS https://ift.tt/jS8H6YD In this webinar, Abhishek Garg will discuss using functional proteomics and multi-omics approaches to explore exhausted/dysfunctional T cell states in various cancers https://ift.tt/uEJhCoO March 22, 2022 at 11:54PM

Amid the Terror of War, Efforts to Keep Science Alive in Ukraine

via The Scientist RSS https://ift.tt/qd60UCS Ukrainian scientists and universities face extraordinary challenges as the Russian invasion continues. https://ift.tt/w0PyuAa March 29, 2022 at 01:02AM

Virus Alters Caterpillars’ Vision to Trick Them into Climbing

via The Scientist RSS https://ift.tt/DwU9pmX A study finds that a baculovirus that infects cotton bollworm larvae changes the expression of genes involved in light perception, driving them to seek heights that could favor viral transmission. https://ift.tt/TFPDefi March 26, 2022 at 02:30AM

Russian Scientists Grapple with an Uncertain Future

via The Scientist RSS https://ift.tt/rs7QWG8 The now month-long invasion of Ukraine has resulted in changes in policies and severances of international scientific collaborations with Russian universities and researchers. The war has also precipitated a moral reckoning for many scientists in Russia. https://ift.tt/TFPDefi March 26, 2022 at 01:31AM

To Mate or Not to Mate? Baboons' Inbreeding Defense Is Biased

via The Scientist RSS https://ift.tt/odT62VA Researchers find that wild baboons are generally good at avoiding inbreeding, but that it's more likely to occur with paternal than maternal relatives. https://ift.tt/TFPDefi March 26, 2022 at 12:54AM

Sino Biological and Ainnocence Partner to Offer Next-Generation Antibody Development CRO Services

via The Scientist RSS https://ift.tt/fd5zNJn Sino Biological, Inc.(“Sino Biological” or the “Company”), a biotechnology company listed on the Shenzhen stock exchange subsidiary ChiNext (SZSE: 301047), which provides biological research reagents and related technical contract research services, is pleased to announce a CRO services partnership with Ainnocence, Inc.  of San Jose, California. https://ift.tt/TFPDefi March 25, 2022 at 07:14PM

No More Messy Notes: Modernizing the Lab Notebook

via The Scientist RSS https://ift.tt/ea6IEdy An electronic laboratory notebook (ELN) keeps data organized and secure, boosting productivity and reproducibility. https://ift.tt/TFPDefi March 25, 2022 at 08:54PM

Tumor Cells on Brink of Death May Trigger Metastasis

via The Scientist RSS https://ift.tt/7Ou9oDR A new study reports that human colon cancer cells at imminent risk of death can instead develop characteristics needed to colonize new parts of the body. https://ift.tt/TFPDefi March 25, 2022 at 06:10PM

Tetanus Immunity Protects Mice Against Pancreatic Cancer

via The Scientist RSS https://ift.tt/HNlFUmM Because most people are vaccinated against tetanus as children, delivering benign bacteria carrying a tetanus antigen into pancreatic tumors makes them visible to memory cells in the immune system, researchers report. https://ift.tt/eGhgzQk March 25, 2022 at 03:00AM

INTEGRA's ASSIST PLUS pipetting robot helps to streamline sample pooling for arbovirus testing

via The Scientist RSS https://ift.tt/6EKQhFO INTEGRA Biosciences’ ASSIST PLUS pipetting robot is helping the Arbovirus Testing Lab at the New Hampshire Public Health Laboratories in Concord, USA, to streamline sample pooling for West Nile and Eastern equine encephalitis virus testing. https://ift.tt/eGhgzQk March 24, 2022 at 08:52PM

Genome Spotlight: Christmas Island Rat (Rattus macleari)

via The Scientist RSS https://ift.tt/Ab9xmaS The near-complete genome of a recently extinct rodent elucidates the potential—and difficulties—of resurrecting species. https://ift.tt/eGhgzQk March 24, 2022 at 07:30PM

Introducing Custom Recombinant Expression Services at the Cutting Edge of Biomolecular Engineering

via The Scientist RSS https://ift.tt/KXjIRtL A turnkey CRO service platform for recombinant protein and antibody expression and production https://ift.tt/eGhgzQk March 24, 2022 at 06:30PM

Brain Implant Allows Completely Paralyzed Patient to Communicate

via The Scientist RSS https://ift.tt/wK16LvH The patient, who has ALS, is able to communicate in complete sentences by deliberately altering his brain’s activity. https://ift.tt/eGhgzQk March 24, 2022 at 06:00PM

Scientists at CNRS using INTEGRA's VOYAGER to speed up their HIV research

via The Scientist RSS https://ift.tt/ri1koV2 https://ift.tt/GKey6N1 March 23, 2022 at 10:52PM

Exploring the World of Glycobiology

via The Scientist RSS https://ift.tt/pDkdIa5 Researchers study sugar modifications to understand health and disease. https://ift.tt/GKey6N1 March 23, 2022 at 09:59PM

Examining Altered Glycobiology in Cancer

via The Scientist RSS https://ift.tt/m0low2R Changes to protein glycosylation play a major role in dictating cancer progression and prognosis, but could they also present biomarkers or therapeutic targets? https://ift.tt/GKey6N1 March 23, 2022 at 09:56PM

A Better Way to Perform PCR

via The Scientist RSS https://ift.tt/GKd6jTZ Researchers turn to ddPCR for accurate nucleic acid quantification during biotherapeutic development. https://ift.tt/GKey6N1 March 23, 2022 at 09:54PM

Wastewater’s Hidden Value for Monitoring Public Health

via The Scientist RSS https://ift.tt/8zbyiUo Learn about wastewater-based epidemiology—from its conception to its present state and into its future. https://ift.tt/GKey6N1 March 23, 2022 at 09:40PM

Streamlined Purification Workflows for Biomolecule Production

via The Scientist RSS https://ift.tt/Kurwx25 Researchers optimize chromatography-based workflows to purify biomolecules at scale. https://ift.tt/GKey6N1 March 23, 2022 at 09:36PM

Customized Commercial Molecular Assay Development

via The Scientist RSS https://ift.tt/6IjQAqX Explore the latest in nucleic acid amplification. https://ift.tt/GKey6N1 March 23, 2022 at 09:29PM

Biophysicist Howard Berg Dies at 87

via The Scientist RSS https://ift.tt/CMlbhwR His research uncovered secrets of motility in E. coli. https://ift.tt/CB42bXd March 22, 2022 at 11:08PM

Reptiles are the Real Bird Brains

via The Scientist RSS https://ift.tt/zvXIC71 A research group argues that a species' number of neurons, rather than brain volume, should serve as indicator of cognitive capacity when studying brain evolution, but some experts voice doubts. https://ift.tt/CB42bXd March 22, 2022 at 09:04PM

A Balancing Act: Requirements for Maintaining Weighing Instruments

via The Scientist RSS https://ift.tt/xOqLngb How to calibrate an analytical balance to meet regulatory requirements https://ift.tt/CB42bXd March 22, 2022 at 07:14PM

Cancer Researcher Donald Pinkel Dies at Age 95

via The Scientist RSS https://ift.tt/IoCmXGJ Unsatisfied by how treatments for childhood leukemia failed to prevent the disease's return, Pinkel combined them all—and virtually cured the disease. https://ift.tt/7KYiAqD March 19, 2022 at 02:10AM

Mass Polio Vaccination Effort Underway in East Africa

via The Scientist RSS https://ift.tt/1rxAoH5 Malawi and its neighbors plan to vaccinate 9.4 million children against polio in the coming week to combat a suspected outbreak. https://ift.tt/7KYiAqD March 19, 2022 at 01:47AM

Neuropathologist John Trojanowski Dies at 75

via The Scientist RSS https://ift.tt/d724FSq His work was pivotal to understanding the mechanisms of neurodegenerative diseases, particularly Alzheimer’s and Parkinson’s. https://ift.tt/7KYiAqD March 19, 2022 at 01:05AM

Replacing Microglia Treats Neurodegenerative Disease in Mice

via The Scientist RSS https://ift.tt/pIswAO6 Researchers find a way to wipe out the brain's immune cell corps and send in new and improved versions. https://ift.tt/4nJdDjx March 18, 2022 at 04:22AM

Fruit Flies Evolve in Time with the Seasons: Study

via The Scientist RSS https://ift.tt/GoTQPlC Researchers find that evolution can operate on extraordinarily fast timescales. https://ift.tt/4nJdDjx March 18, 2022 at 02:28AM

Power Shortages Dim Results of Many Neuroimaging Studies

via The Scientist RSS https://ift.tt/DtVYvlw Low participant numbers render the results of many studies based on brain scans unreliable, an analysis finds. https://ift.tt/iTtJeEm March 18, 2022 at 12:20AM

Bacteria in the Lungs Can Regulate Autoimmunity in Rat Brains

via The Scientist RSS https://ift.tt/dzQ0nux Making specific alterations to the bacterial population in a rat’s lungs either better protects the animals against multiple sclerosis–like symptoms or makes them more vulnerable, a study finds—the first demonstration of a lung-brain axis. https://ift.tt/iTtJeEm March 17, 2022 at 11:30PM

Study: Sickle Cell Mutation Driven by Pressure, Not Random Chance

via The Scientist RSS https://ift.tt/tOdyLFs New research finds that the appearance of the HbS mutation, which protects against malaria but leads to sickle cell disease when present in two copies, was more common in sperm samples from men in Ghana, where malaria risk is high, than Europeans. https://ift.tt/iTtJeEm March 17, 2022 at 06:04PM

Neurons Damaged in Dementia Recognize Interruptions to Patterns

via The Scientist RSS https://ift.tt/JxXhP7W A new study reveals a network of neurons that, when disrupted, impairs adaptation to new circumstances in several types of dementia. https://ift.tt/iTtJeEm March 17, 2022 at 02:00AM

Empty or Full: Separating Therapeutically Viable Viral Vectors

via The Scientist RSS https://ift.tt/fwusqx2 How to detect impurities during gene therapy vector production https://ift.tt/oM0V8jO March 16, 2022 at 10:23PM

A Life-or-Death Situation: Determining Cell Viability

via The Scientist RSS https://ift.tt/CgJLtdz Learn how to match cell viability assays with downstream applications. https://ift.tt/oM0V8jO March 16, 2022 at 10:18PM

Notable Science Quotes

via The Scientist RSS https://ift.tt/ABnhlxb Reviving the Cancer Moonshot, disentangling the microbiome's effect in cancer, the observer effect, and more https://ift.tt/oM0V8jO March 16, 2022 at 09:30AM

Living the Life Pandemic

via The Scientist RSS https://ift.tt/V72xAe0 The first part of 2022 is giving us a glimpse of humanity’s future relationship with COVID-19. https://ift.tt/oM0V8jO March 16, 2022 at 09:30AM

Identifying Biomarkers to Guide Cancer Immunotherapy

via The Scientist RSS https://ift.tt/o1HRZML An expert panel will discuss the cutting-edge technologies they used to identify novel biomarkers that predict patient responses to immunotherapy. https://ift.tt/oM0V8jO March 15, 2022 at 11:36PM

Oust the Mouse: A Plan to Reduce Mammal Use in Drug Development

via The Scientist RSS https://ift.tt/OYljrWZ The Scientist spoke to Mount Desert Island Biological Laboratory's Jim Strickland about the institute's new MDI Bioscience initiative to perform more drug testing and development in nonmammalian models. https://ift.tt/tV9mwsp March 15, 2022 at 06:00PM

Voles Trim Tall Grass to Prevent Attacks

via The Scientist RSS https://ift.tt/i0I4EFg Mongolian rodents join the ranks of earthworms and beavers as known ecosystem engineers. https://ift.tt/tV9mwsp March 15, 2022 at 02:29AM

Infographic: Nitrogen-Fixing Bacteria Live Inside Seagrass Roots

via The Scientist RSS https://ift.tt/KBgNHlc Researchers can now explain how some marine plants obtain their nitrogen. https://ift.tt/SaFPsHm March 14, 2022 at 09:30AM