Skip to main content

Posts

Showing posts from August, 2022

Brush Up: Humanized Mice: More than the Sum of Their Parts

via The Scientist RSS https://ift.tt/DJPakwf Scientists study human health in vivo with modified mice that molecularly mimic human biology. https://ift.tt/x4MUyCq August 31, 2022 at 06:24PM

The Scientist Speaks - Filling in the Gaps: Sequencing the Entire Human Genome

via The Scientist RSS https://ift.tt/povV5iK Karen Miga discusses how she and collaborators sequenced the missing parts of the human genome almost two decades after the first Human Genome Project published its results. https://ift.tt/x4MUyCq August 30, 2022 at 10:21PM

Major, Groundbreaking Increase in Hype in Grant Applications

via The Scientist RSS https://ift.tt/W1QM9sT Projects funded by the National Institutes of Health increasingly employ subjective and promotional language in describing research, a study finds. https://ift.tt/x4MUyCq August 31, 2022 at 01:41AM

U.K. Health Authority Investigates Epilepsy Drug's Link to Autism

via The Scientist RSS https://ift.tt/VUZgHKF The Medicines and Healthcare products Regulatory Agency's investigation comes after a study showed prenatal exposure to topiramate roughly triples a child's likelihood of having autism or intellectual disability. https://ift.tt/x4MUyCq August 31, 2022 at 01:19AM

Doppelgängers Similar in Looks and DNA: Study

via The Scientist RSS https://ift.tt/ROSMglz Look-alikes are also more likely to share lifestyle traits. https://ift.tt/x4MUyCq August 31, 2022 at 12:15AM

Experimental Design and Sample Processing for Metabolomics

via The Scientist RSS https://ift.tt/k87L0zR Shama Naz will discuss how controlling pre-analytical factors and selecting appropriate analytical tools improves the outcome of metabolomics experiments. https://ift.tt/x4MUyCq August 30, 2022 at 11:13PM

Transform Clinical Trial Design to Prioritize Patients

via The Scientist RSS https://ift.tt/j4Ml96a Discover how to decentralize clinical trials and assess patient health remotely.   https://ift.tt/7V8FXsg August 27, 2022 at 01:15AM

Federal Investigators Probe Possible Misconduct in Pig Research

via The Scientist RSS https://ift.tt/9IuAjB6 A quintet of research papers, all involving subjecting newborn piglets to brain damage, have been retracted because the data can’t be substantiated. https://ift.tt/7V8FXsg August 30, 2022 at 08:30PM

Genotyping Made Easy with Automation

via The Scientist RSS https://ift.tt/mQIrabX https://ift.tt/7V8FXsg August 30, 2022 at 07:20PM

Technique Talk: Developing Spatial Multiomic Maps

via The Scientist RSS https://ift.tt/WfuHz62 Rafael Kramann will discuss spatial transcriptome and epigenome changes to identify injury, repair, and remodeling in myocardial infarction. https://ift.tt/7V8FXsg August 29, 2022 at 11:04PM

DNA Analyses Illuminate Origins of Farming, Ancestral Languages

via The Scientist RSS https://ift.tt/VaUCNrG The findings suggest a new hypothesis of Indo-European language evolution. https://ift.tt/IPFhudx August 27, 2022 at 01:17AM

AAAS Shutters Its Center for Public Engagement

via The Scientist RSS https://ift.tt/xLWSrUM The center oversaw programs such as the Mass Media Science & Engineering Fellowship, many of which will continue. https://ift.tt/IPFhudx August 27, 2022 at 01:05AM

It’s Not Just You: Lockdowns Had Us Living in “Blursday,” Study Says

via The Scientist RSS https://ift.tt/LytC7Tg The Scientist spoke with Maximilien Chaumon about his database showing how COVID-19 related lockdowns warped more 2,800 people’s perception of time. https://ift.tt/IPFhudx August 27, 2022 at 12:19AM

Scientific Breakthroughs with Stem Cells

via The Scientist RSS https://ift.tt/zFIZPmb Discover the various ways scientists bolster stem cells to understand and cure disease. https://ift.tt/IPFhudx August 26, 2022 at 09:22PM

Quality Control for In Vitro Transcription RNA Synthesis

via The Scientist RSS https://ift.tt/YXIQTU6 Parallel capillary electrophoresis is an extremely sensitive, reliable, and high throughput method for checking RNA synthesis quality. https://ift.tt/IPFhudx August 25, 2022 at 07:09PM

No More Paywalls on Federally Funded Research: White House

via The Scientist RSS https://ift.tt/dWYEUsO The Biden administration will by 2026 require that all publicly funded work be deposited in designated repositories immediately on publication. https://ift.tt/c7Opj2M August 26, 2022 at 02:30AM

Researchers Fuse Mouse Chromosomes in Scientific First

via The Scientist RSS https://ift.tt/3LZDnGc The findings will likely help elucidate the effects of chromosome fusions, which can cause disease but have also contributed to evolution. https://ift.tt/c7Opj2M August 26, 2022 at 02:03AM

Ancient Mummies’ Lousy View of the Past

via The Scientist RSS https://ift.tt/5sGe9iF Researchers develop method to study ancient human DNA preserved by head lice. https://ift.tt/c7Opj2M August 26, 2022 at 12:08AM

Book Excerpt from When Animals Dream

via The Scientist RSS https://ift.tt/H8Q1FMS In Chapter 1, “The Science of Animal Dreams,” author David M. Peña-Guzmán relays the history of researchers digging into the mental realities of nonhuman brains. https://ift.tt/sXyvVzB August 25, 2022 at 09:31PM

Genome Spotlight: Edith's Checkerspot Butterfly (Euphydryas editha)

via The Scientist RSS https://ift.tt/sVA362y A high-quality genome sequence for this versatile insect will likely aid eco-evolutionary research. https://ift.tt/sXyvVzB August 25, 2022 at 07:30PM

How a Specific Gut Bacterium May Cause Type 1 Diabetes

via The Scientist RSS https://ift.tt/TL7QoFx A bacterium that produces an insulin-like peptide can give mice type 1 diabetes and seem to predict the onset of the disease in humans, a study finds. https://ift.tt/sXyvVzB August 25, 2022 at 06:06PM

Science Snapshot: An Arm and A Leg

via The Scientist RSS https://ift.tt/nHLxaCi 3D modeling of 7 million-year-old hominin bones hints at bipedality occurring earlier than previously thought. https://ift.tt/sXyvVzB August 25, 2022 at 02:13AM

Does everyone in your lab follow the most basic and important biosafety rules?

via The Scientist RSS https://ift.tt/o4rzhxM Does everyone in your lab follow the most basic and important biosafety rules? https://ift.tt/sXyvVzB August 25, 2022 at 12:20AM

Brush Up: Hematopoietic Stem Cells and Their Role in Development and Disease Therapy

via The Scientist RSS https://ift.tt/ZctBQpX https://ift.tt/sXyvVzB August 24, 2022 at 06:05PM

Hematopoietic Stem Cells and Their Role in Development and Disease Therapy

via The Scientist RSS https://ift.tt/2eGb6jX https://ift.tt/KltoC8A August 24, 2022 at 06:05PM

For Frogs, Bigger Brains Mean Worse Camouflage

via The Scientist RSS https://ift.tt/HVZu5Q4 Frogs invest in cognitive capacity to avoid predators—up until there are too many hungry snakes around for the evolutionary strategy to pay off. https://ift.tt/KltoC8A August 24, 2022 at 12:55AM

2D Genetic Map of Prostate Cells Charts Cancer Growth

via The Scientist RSS https://ift.tt/OFLD4qv An in situ map of copy number variations in prostate tissue reveals that purportedly cancerous genomic changes frequently occur in the healthy tissue surrounding tumors. https://ift.tt/KltoC8A August 24, 2022 at 12:42AM

Small Changes, Big Consequences

via The Scientist RSS https://ift.tt/qKsb7yO To understand the mechanisms behind severe COVID-19, researchers identified common COVID-19 genetic risk variants that affect immune cell function. https://ift.tt/KltoC8A August 23, 2022 at 07:55PM

Modernizing Drug Discovery with Flow Cytometry

via The Scientist RSS https://ift.tt/ckWwQmU https://ift.tt/KltoC8A August 24, 2022 at 12:00AM

Electrically Zapping Specific Brain Regions Can Boost Memory

via The Scientist RSS https://ift.tt/fCjW2BD Low-intensity electrical stimulation allows older adults to better recall a list of words for at least a month following the treatment, a study finds, providing further evidence for the debated idea that electrical stimulation can enhance cognitive performance. https://ift.tt/vKXL8Ne August 23, 2022 at 02:40AM

In Search of the Best Milk Recipe for Preemies’ Gut Bacteria

via The Scientist RSS https://ift.tt/glZV3Ww Milk fortifiers of human origin show no evident advantage in the development of the gut microbiota of premature infants over fortifiers derived from cows, while the intake of the mother’s own milk does, two studies suggest. https://ift.tt/vKXL8Ne August 23, 2022 at 01:47AM

Disease and Treatment Response Mechanisms in Drug Discovery

via The Scientist RSS https://ift.tt/Wtp2cb1 Explore the latest studies in biomarker discovery, mechanisms of action, patient stratification, and response monitoring. https://ift.tt/vKXL8Ne August 16, 2022 at 07:31PM

Anthony Fauci Announces Departure from NIAID, Advisory Roles

via The Scientist RSS https://ift.tt/hYUHsnd The 81-year-old director says that he will step back from his positions this December, but that he will continue working to advance science and public health. https://ift.tt/vKXL8Ne August 23, 2022 at 12:30AM

Dogs Cry Tears of Joy: Study

via The Scientist RSS https://ift.tt/ij5lTmD Pet dogs produce a larger volume of tears when they are reunited with their owners than with acquaintances, possibly because of surging oxytocin levels--findings that could be the first evidence of emotional crying in nonhuman animals. https://ift.tt/vKXL8Ne August 22, 2022 at 08:30PM

The Double Life of a Fungus: Defends Beetle, Attacks Plant

via The Scientist RSS https://ift.tt/xODWPNJ Tortoise leaf beetles enjoy the protection the fungus provides from insect predators such as ants, then carry the microbe to a mutual plant host, which their fungal symbiont infects. https://ift.tt/IvaJD5k August 20, 2022 at 02:00AM

Scans of Sundry Variant Types Uncover Autism-Linked Genes

via The Scientist RSS https://ift.tt/gxLYCtI Troves of sequencing data reveal genes tied to autism through different variant types, providing a more complete picture of the condition's genetic roots and new clues to its heterogeneity. https://ift.tt/BrbaKm7 August 20, 2022 at 12:46AM

Opinion: A Dog Has Caught Monkeypox from One of Its Owners, Highlighting Risk of the Virus Infecting Pets and Wild Animals

via The Scientist RSS https://ift.tt/5glmtjP The monkeypox virus can easily spread between humans and animals. A veterinary virologist explains how the virus could go from people to wild animals in the US—and why that could be a problem.  https://ift.tt/BrbaKm7 August 19, 2022 at 11:54PM

Artificial Sweeteners Alter Gut Bacteria in Humans

via The Scientist RSS https://ift.tt/d2fahqs When consumed for as little as two weeks, common alternatives to sugar affect intestinal bacterial communities, with some reducing the body's ability to regulate blood glucose levels, a study finds. https://ift.tt/BrbaKm7 August 19, 2022 at 08:30PM

Internal Clock Disruptions Increase Colon Cancer Risk in Mice

via The Scientist RSS https://ift.tt/eBxTzuk Disturbing circadian rhythms in organoids and mice increases intestinal tumor growth, findings that may explain a recent rise in colon cancer among young adults, the researchers behind the work say. https://ift.tt/BrbaKm7 August 19, 2022 at 08:05PM

Agreement Reached on Research Assessment Reforms

via The Scientist RSS https://ift.tt/AZedPV4 The document, which was facilitated by the European Commission, establishes new benchmarks regarding how assessing research quality should be performed. https://ift.tt/BrbaKm7 August 19, 2022 at 07:02PM

NIH Fails to Enforce Rules for Reporting Clinical Trial Results

via The Scientist RSS https://ift.tt/8ziPK2R A review by the US Office of Inspector General found that only about half of the scientists running clinical trials funded by the NIH in 2019 and 2020 appropriately recorded their findings in a federal database, as is legally required. https://ift.tt/BrbaKm7 August 19, 2022 at 01:10AM

CDC Restructuring Aims to Improve Timeliness and Accountability

via The Scientist RSS https://ift.tt/WKA7SUf Director Rochelle Walensky said the agency's handling of the COVID-19 pandemic fell short and outlined plans to reorganize and strengthen its response to future public health threats. https://ift.tt/BrbaKm7 August 19, 2022 at 12:30AM

Uncovering Leprosy’s Genetic Recipe for Success

via The Scientist RSS https://ift.tt/sn69h4o Researchers identify what makes certain people more likely to contract leprosy than others. https://ift.tt/BrbaKm7 August 17, 2022 at 10:12PM

The Neuroscience Behind Why Mosquitoes Always Find You

via The Scientist RSS https://ift.tt/GEmHs3v Neurons in mosquito antennae can express more than one olfactory receptor at a time, a redundancy that likely ensures they don't lose a potential host's scent. https://ift.tt/UWjYyVk August 18, 2022 at 08:30PM

Science Snapshot: Reversing an Invasion of Paradise

via The Scientist RSS https://ift.tt/scOxirz After years of work, conservationists have successfully eliminated two invasive rat species from the Tetiaroa Atoll in French Polynesia. https://ift.tt/UWjYyVk August 18, 2022 at 02:37AM

The Energetic Cost of Chewing May Have Shaped Hominin Evolution

via The Scientist RSS https://ift.tt/c6vQos2 The simple act of chewing gum can raise the body’s metabolic rate by as much as 15 percent, a study finds. https://ift.tt/UWjYyVk August 18, 2022 at 12:20AM

Prokaryotes Are Capable of Learning to Recognize Phages

via The Scientist RSS https://ift.tt/XMKJmsw Immune defense genes in bacteria and archaea can identify viral proteins, a study finds, revealing similarities between the immune systems of prokaryotic and eukaryotic organisms. https://ift.tt/Y0NUCSm August 17, 2022 at 08:30PM

Innovating Clinical Trials Q&A

via The Scientist RSS https://ift.tt/Pgc1dbn In this webinar event, Taras Carpiac from Amgen will answer questions that delve deeper into the entire podcast series. https://ift.tt/Y0NUCSm August 17, 2022 at 07:49PM

Innovating Clinical Trials - A Special 4-Part Podcast Series

via The Scientist RSS https://ift.tt/LpoNHjm Welcome to Innovating Clinical Trials, a special edition podcast series produced by The Scientist’s Creative Services Team. https://ift.tt/Y0NUCSm August 17, 2022 at 07:39PM

How COVID-19 Affects Pregnancy

via The Scientist RSS https://ift.tt/4gh5Hje Evidence thus far shows the pregnant people infected with SARS-CoV-2 are at higher risk for severe disease and death, as well as complications in their pregnancies. https://ift.tt/Y0NUCSm August 17, 2022 at 01:02AM