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Showing posts from September, 2022

Brush Up: What Is Stemness and Pluripotency?

via The Scientist RSS https://ift.tt/prguXem Scientists study pluripotent stems cells to understand early development and how to use them in regenerative medicine, disease modeling, and drug discovery. https://ift.tt/1EW0xGL September 30, 2022 at 05:52PM

How To Select the Appropriate Biomolecular Imager

via The Scientist RSS https://ift.tt/T0jJuWD Tips for matching the right imager to bioimaging workflows https://ift.tt/1EW0xGL September 26, 2022 at 11:18PM

Brush Up: What Is Stemness and Pluripotency?

via The Scientist RSS https://ift.tt/prguXem https://ift.tt/1EW0xGL September 30, 2022 at 05:52PM

Different Genes Influence Lifespan in Male and Female Mice

via The Scientist RSS https://ift.tt/ouBxe9a Researchers say there may be similar genes in humans whose effects on lifespan vary by sex. https://ift.tt/1EW0xGL September 29, 2022 at 11:30PM

The Unscientific King: Charles III’s History Promoting Homeopathy

via The Scientist RSS https://ift.tt/uEU9L48 King Charles III has a long history of promoting homeopathic or alternative medical treatments not supported by scientific evidence. https://ift.tt/vfZJNs3 September 29, 2022 at 08:35PM

Multiple Possible Causes of Long COVID Come into Focus

via The Scientist RSS https://ift.tt/YAhqudF Recent studies have lent support for a variety of hypotheses explaining the debilitating symptoms affecting millions of people after SARS-CoV-2 infection.   https://ift.tt/vfZJNs3 September 29, 2022 at 02:50AM

New Alzheimer’s Drug Slows Cognitive Decline in Clinical Trial

via The Scientist RSS https://ift.tt/TbzfF4u The Biogen-developed treatment, called lecanemab, appears to have a more clear-cut effect on slowing the disease than the company’s previous Alzheimer’s drug, Aduhelm. https://ift.tt/vfZJNs3 September 29, 2022 at 02:38AM

Understanding Biopharma Market Trends and the Innovations That Drive Them

via The Scientist RSS https://ift.tt/xMRoO5q Explore the latest science shaping the healthcare sector. https://ift.tt/vfZJNs3 September 26, 2022 at 11:10PM

The Deepwater Horizon Oil Spill’s Hidden Impacts on Mahi-Mahi      

via The Scientist RSS https://ift.tt/I5aCJiG Mahi-mahi were more likely to be eaten and less likely to spawn after being exposed to sublethal concentrations of oil, raising concerns about the risks oceanic drilling pose to life in the ocean. https://ift.tt/vfZJNs3 September 28, 2022 at 10:56PM

2022 Lasker Award Winners Announced

via The Scientist RSS https://ift.tt/7bvAa0J This year’s awards recognize work on integrins, noninvasive prenatal screening, and COVID-19 data-tracking. https://ift.tt/vfZJNs3 September 28, 2022 at 08:54PM

Most Archaea and Bacteria are Nameless. SeqCode Could Change That

via The Scientist RSS https://ift.tt/vzf1WLY The Scientist spoke with microbiologist William Whitman about a new system of nomenclature for prokaryotic organisms that can’t be cultured. https://ift.tt/6J48Yzx September 28, 2022 at 03:00AM

Researchers in Ian’s Path Brace for the Storm

via The Scientist RSS https://ift.tt/tOGTAsC With their laboratories prepared as best as possible for what's now a Category 3 hurricane, all scientists in Florida can do now is wait. https://ift.tt/6J48Yzx September 28, 2022 at 02:21AM

Lawyer Turned Stem Cell Advocate Susan Solomon Dies at 71

via The Scientist RSS https://ift.tt/sZ12yKL Her passion came from her son’s struggle with type 1 diabetes and the inability to find new treatments. https://ift.tt/6J48Yzx September 27, 2022 at 11:34PM

Ford Foundation Sunsets Diversity Fellowships

via The Scientist RSS https://ift.tt/v2DTbp0 For more than 50 years, the program has served as a pipeline to get more scholars of color into academic institutions. https://ift.tt/6J48Yzx September 27, 2022 at 10:46PM

Drug Spurs Neuron Growth in Mice with Chronic Spinal Cord Injury

via The Scientist RSS https://ift.tt/S5HcbPd A protein duo increases transcription of growth-related genes to enhance axon regeneration and boost plasticity, a study finds—but failed to improve mobility. https://ift.tt/ciej9Ll September 27, 2022 at 04:03PM

Registry Review Casts Doubt on Causal Link Between Maternal Infection and Autism

via The Scientist RSS https://ift.tt/5RskuaU Maternal infection during pregnancy may be associated with autism, as previous studies have suggested—but perhaps not in a causal way. https://ift.tt/ciej9Ll September 27, 2022 at 02:10AM

Targeting Leukemia with T Cells That Avoid Self-Destruction

via The Scientist RSS https://ift.tt/iwG8Y6r Researchers found that naturally-occurring CD7-negative T cells avoid self-destruction and are good effectors in CAR T therapy for T cell blood cancers. https://ift.tt/ciej9Ll September 26, 2022 at 08:43PM

Armored CAR T Cells Break Through Immune Suppression in Solid Tumors

via The Scientist RSS https://ift.tt/WhVxrYm Researchers determined the safety and antitumor ability of genetically engineered CAR T cells that circumvent immune suppression in a prostate cancer phase I clinical trial. https://ift.tt/ciej9Ll September 26, 2022 at 08:36PM

Breast Cancer Cells Retrain T Cells to Invade Specific Tissues

via The Scientist RSS https://ift.tt/KQA5SPU Scientists discover tumor-associated T cells that drive breast cancer metastasis to lymph nodes. https://ift.tt/ciej9Ll September 26, 2022 at 06:30PM

Slow Vaccine Delivery May Maximize Immune Response

via The Scientist RSS https://ift.tt/CSyTRad A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more effective antibody production against HIV in rhesus monkeys, a study finds. https://ift.tt/XAafJOS September 24, 2022 at 05:30AM

“Extreme Inequality” Entrenched in Academic Hiring: Study

via The Scientist RSS https://ift.tt/bCPomIq https://ift.tt/XAafJOS September 24, 2022 at 02:54AM

Research Pinpoints the Neurons Behind Feeling Ill

via The Scientist RSS https://ift.tt/Q6qB2o8 Specific neurons in the brainstem control sickness behaviors not directly caused by a pathogen, such as tiredness and lack of appetite, a mouse study finds. https://ift.tt/LPWMFpD September 24, 2022 at 12:05AM

Exposed: Environmental Echoes in Health - A Special Podcast Series

via The Scientist RSS https://ift.tt/NXoRmB7 Epigenetic experts discuss how environment and diet leave lasting impressions on the human genome. https://ift.tt/LPWMFpD September 23, 2022 at 08:24PM

Technique Talk: Turning the PAGE—The Dos and Don’ts of Protein Electrophoresis and Western Blotting

via The Scientist RSS https://ift.tt/mWBEfiL In this webinar, Kelly Wolfe will discuss innovations that streamline western blotting workflows. https://ift.tt/LPWMFpD September 22, 2022 at 08:49PM

Technique Talk: Turning the PAGE—The Dos and Don’ts of Protein Electrophoresis and Western Blotting

via The Scientist RSS https://ift.tt/Xwtnia8 In this webinar, Kelly Wolfe will discuss innovations that streamline western blotting workflows. https://ift.tt/LPWMFpD September 22, 2022 at 08:00PM

Are We In the Midst of a Silent Mass Extinction?

via The Scientist RSS https://ift.tt/dBzlTwP A new modeling technique aims to help scientists and policymakers detect declines in genetic diversity based on habitat loss. https://ift.tt/LPWMFpD September 23, 2022 at 01:36AM

Explore the genetics revolution in medicine.

via The Scientist RSS https://ift.tt/eQYptwP Explore the genetics revolution in medicine. https://ift.tt/qxC0JE7 September 19, 2022 at 08:23PM

Streamlining Pharma Quality Control Workflows with Best Practices

via The Scientist RSS https://ift.tt/Pkmu5EK A concise guide to maintaining compliance standards for pipetting https://ift.tt/qxC0JE7 September 22, 2022 at 09:56PM

Genome Spotlight: C-fern (Ceratopteris richardii)

via The Scientist RSS https://ift.tt/VYkpbPt Sequences for the model organism and two of its kin reveal how these plants got their oversized genomes. https://ift.tt/qxC0JE7 September 22, 2022 at 07:30PM

Fast Amplification-Based NGS Library Preparation

via The Scientist RSS https://ift.tt/CXP7V4D In this webinar, Jennifer Silverman and Kan Saito will discuss using rapid genome and transcriptome amplification kits on low input samples for next-generation sequencing. https://ift.tt/qxC0JE7 September 21, 2022 at 10:57PM

High-Tech Solutions to Drug Characterization Challenges

via The Scientist RSS https://ift.tt/6OCs4D0 When performing comparability studies on biosimilar drugs, modern instruments simplify the process. https://ift.tt/qxC0JE7 September 22, 2022 at 06:46PM

Researchers Assess Setbacks After Hurricane Fiona

via The Scientist RSS https://ift.tt/DTx5SNH Some areas of Puerto Rico have been hit by flooding and high winds, but long power outages are also impeding scientists’ work. https://ift.tt/qxC0JE7 September 22, 2022 at 02:59AM

Efficient Pluripotent Stem Cell Preparation for Downstream Applications

via The Scientist RSS https://ift.tt/Qc4PrAl Explore how to minimize error while dissociating cells and spheroids. https://ift.tt/qxC0JE7 September 22, 2022 at 12:32AM

Past Malaria Surges Linked to Amphibian Die-off

via The Scientist RSS https://ift.tt/fNaJQjz A study suggests that pathogens affecting other species can indirectly harm human health. https://ift.tt/FswylKm September 21, 2022 at 08:50PM

Fungal Cold Adaptation Linked to Protein Structure Changes: Study

via The Scientist RSS https://ift.tt/tUp9CL1 Environmental pressure seems to spawn changes in the intrinsically disordered regions of enzymes in polar yeasts, allowing them to adapt to extreme cold. https://ift.tt/FswylKm September 21, 2022 at 02:30AM

Capturing Brain Complexity in Assembloids

via The Scientist RSS https://ift.tt/IC7mrNY In this webinar, Jimena Anderson and Jens Schwamborn will describe the next-generation brain organoids that combine multiple brain regions and cell types in 3D cultures. https://ift.tt/FswylKm September 21, 2022 at 12:18AM

Uganda Declares Ebola Outbreak After Fatality

via The Scientist RSS https://ift.tt/J65LlMu The outbreak of the Sudan strain of ebolavirus, which includes eight other suspected cases, is the first to hit Uganda in more than a decade. https://ift.tt/FswylKm September 20, 2022 at 11:26PM

Union of Concerned Scientists Cofounder Kurt Gottfried Dies at 93

via The Scientist RSS https://ift.tt/G6dV3k9 The Cornell University physicist was an advocate on issues such as nuclear weapons and climate change. https://ift.tt/FswylKm September 20, 2022 at 08:11PM

Getting Started with Glycan Screening

via The Scientist RSS https://ift.tt/FPA9Zyk In this webinar, August Estabrook will discuss how to use immunofluorescence to screen for glycans. https://ift.tt/8CnbLyM September 16, 2022 at 08:26PM

Thermo Fisher DNA Collection Kits Purchased by Police in Tibet

via The Scientist RSS https://ift.tt/GMYqFzt Government documents suggest that Chinese authorities continue to use Thermo Fisher supplies in mass collection of DNA from minority groups. https://ift.tt/8CnbLyM September 20, 2022 at 02:45AM

Enhanced Reliability in CAR T Cell Production

via The Scientist RSS https://ift.tt/KPRwWA5 A modular, closed system reduces errors and speeds up CAR T bioprocessing. https://ift.tt/8CnbLyM September 15, 2022 at 08:16PM

Repeated El Niño Events Could Spark Big Ecological Shifts

via The Scientist RSS https://ift.tt/EBAk54z Five major El Niño events per century could lead to fewer fishes that thrive in cold water and more terrestrial birds in eastern coastal ecosystems. https://ift.tt/8CnbLyM September 19, 2022 at 09:16PM

T Cells Ward Off Aging With Help From Their Friends

via The Scientist RSS https://ift.tt/N4ydDmz Immune cells deliver packages of telomeres to T cells, helping them retain their virus-fighting function over time, research suggests. https://ift.tt/gyu40VG September 17, 2022 at 02:44AM

Constipation’s Effect on Scorpion Sex Garners Biology Ig Nobel

via The Scientist RSS https://ift.tt/kJ0Np4a Other winners of this year’s prizes include research on the physics of ducklings and the therapeutic potential of ice cream. https://ift.tt/gyu40VG September 17, 2022 at 02:44AM

Historic Adaptations May Now Make Us Susceptible to Disease

via The Scientist RSS https://ift.tt/Y0fb4L6 Researchers made the find using an algorithm that purportedly distinguishes between mutations that were selected for and those that came along for the ride by coincidence, a feat that has long eluded scientists. https://ift.tt/gyu40VG September 17, 2022 at 02:40AM

Seeing Science: How to Visually Explain Complex Concepts

via The Scientist RSS https://ift.tt/rhFaYB7 Scientists turn to an easy, plug-and-play platform to visually translate their work. https://ift.tt/4ItKbhm September 16, 2022 at 08:51PM

Immunotherapy Treats Fibrosis in Mice

via The Scientist RSS https://ift.tt/s3uRw70 Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents. https://ift.tt/4ItKbhm September 16, 2022 at 02:04AM

Brush Up: What Is Bisulfite Sequencing and How Do Researchers Use It to Study DNA Methylation?

via The Scientist RSS https://ift.tt/XcWoGU8 Prior to DNA methylation sequencing, researchers treat their samples with sodium bisulfite to distinguish methylated cytosine from unmethylated cytosine. https://ift.tt/4ItKbhm September 15, 2022 at 11:12PM

What Is Bisulfite Sequencing and How Do Researchers Use It to Study DNA Methylation?

via The Scientist RSS https://ift.tt/RT5vYqs https://ift.tt/4ItKbhm September 15, 2022 at 11:12PM

Science Snapshot: Fine Feathered Foes

via The Scientist RSS https://ift.tt/4cUxDAH Australians are resorting to increasingly drastic measures to keep cockatoos out of their garbage bins. https://ift.tt/d7IVlYJ September 15, 2022 at 02:10AM