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Showing posts from October, 2022

Science Snapshot: Milking It

via The Scientist RSS https://ift.tt/7qTWO1u This image took 2nd place at the 2022 Nikon Small World Photomicrography Competition. https://ift.tt/1GntAui October 31, 2022 at 03:40PM

Science Snapshot: Show of Hands

via The Scientist RSS https://ift.tt/hgeuEYc This image took the top prize at the 2022 Nikon Small World Photomicrography Competition. https://ift.tt/Z4muxdy October 29, 2022 at 01:27AM

Skin Bacteria May Trigger Lupus: Mouse Study

via The Scientist RSS https://ift.tt/ywQiheK https://ift.tt/Z4muxdy October 28, 2022 at 11:30PM

Younger Scientists Are More Innovative, Study Finds

via The Scientist RSS https://ift.tt/MvELAOr On average, researchers’ impact dropped by a half to two-thirds over their careers. https://ift.tt/fwQDT47 October 28, 2022 at 07:59PM

The Scientist Speaks - Exploring the Secrets to Longevity and Cancer Resistance in Mole-Rats

via The Scientist RSS https://ift.tt/xtFJ9ia Vera Gorbunova discusses what naked and blind mole-rat cells reveal about aging and cancer resistance mechanisms.  https://ift.tt/fwQDT47 October 24, 2022 at 08:36PM

New NAS Awards Honor Science Communication in “Post-Truth World”

via The Scientist RSS https://ift.tt/2AKOrfj The Scientist speaks with paleoecologist Jaqueline Gill, who won one of the 24 awards recognizing efforts to communicate scientific issues to the general public. https://ift.tt/fwQDT47 October 28, 2022 at 01:35AM

COVID-19: Lessons Learned 

via The Scientist RSS https://ift.tt/D4ahq8b An expert panel will discuss what researchers have learned from the COVID-19 pandemic and what lessons remain for the future.  https://ift.tt/fwQDT47 October 27, 2022 at 08:42PM

Genome Spotlight: Freshwater Angelfish (Pterophyllum scalare)

via The Scientist RSS https://ift.tt/cQDOgYh A high school student uses crowdfunding to produce the first genome assembly for this popular aquarium species, underscoring the increasing feasibility of whole-genome sequencing. https://ift.tt/M9C8XjU October 27, 2022 at 07:30PM

LabTalk Podcast - Transporting Laboratories into the Future with Smart Technology 

via The Scientist RSS https://ift.tt/56eo1uG Experts discuss how smart devices change research for the better. https://ift.tt/M9C8XjU October 27, 2022 at 06:11PM

Battling cancer with INTEGRA Biosciences’ pipette controllers

via The Scientist RSS https://ift.tt/IQWNuBF Researchers at Tübingen University Hospital, Germany, are using PIPETBOY acu 2 pipette controllers and the VACUSIP portable aspiration system from INTEGRA Biosciences to help them identify new tumor cell targets.  https://ift.tt/M9C8XjU October 27, 2022 at 06:01PM

Turtle Vocalizations Reframe Origins of Auditory Communication

via The Scientist RSS https://ift.tt/hcAB790 Sounds made by more than 50 vertebrates previously thought to be mute push back the origin of this type of communication by at least 100 million years, a study finds. https://ift.tt/M9C8XjU October 27, 2022 at 01:09AM

Considerations for Gene Therapy Manufacturing Strategies 

via The Scientist RSS https://ift.tt/bgwho6L Discover tips for setting up and optimizing adeno-associated virus production. https://ift.tt/M9C8XjU October 25, 2022 at 01:45AM

Phenotypic Variation in Cancer Cells Often Not Due to Mutations

via The Scientist RSS https://ift.tt/rfM0sDn Most differences in gene expression among cells within a tumor are likely due to environment or noise, a study suggests.  https://ift.tt/M9C8XjU October 26, 2022 at 08:30PM

Fungal Pathogens Flourish in the Pandemic’s Shadow 

via The Scientist RSS https://ift.tt/VluQsy2 The World Health Organization’s first ever fungal priority pathogens list highlights the growing threat of fungal diseases and antifungal resistance. https://ift.tt/RpvQsaW October 26, 2022 at 02:30AM

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via The Scientist RSS https://ift.tt/HUMdlkJ https://ift.tt/lsGX42T October 25, 2022 at 11:29PM

Some Honey Bee Swarms Generate Electrical Charges Stronger Than Storms

via The Scientist RSS https://ift.tt/ZBHhVb5 The small charges carried by individual insects can add up, a study finds, with larger swarms generating substantial electrical fields. https://ift.tt/yITrODB October 25, 2022 at 12:20AM

Ancient Viral DNA Helps Mouse Brains Fight Infection

via The Scientist RSS https://ift.tt/5XRFzEo Mammals that give birth to live young may have evolved to make use of the remnants of viruses in their genomes to ward off pathogens, a study suggests.  https://ift.tt/yITrODB October 24, 2022 at 11:12PM

Exploring the Secrets to Longevity and Cancer Resistance in Mole-Rats

via The Scientist RSS https://ift.tt/MisO1Wb https://ift.tt/yITrODB October 24, 2022 at 08:36PM

Advancing CAR T Cell Research and Development 

via The Scientist RSS https://ift.tt/MdPAp3T How to develop the best CAR T cell product for preclinical use. https://ift.tt/yITrODB October 20, 2022 at 07:44PM

Demystifying Single Cell Sequencing 

via The Scientist RSS https://ift.tt/ZqNkXV3 New single cell technologies make previously unattainable discoveries a reality. https://ift.tt/3NzngGP October 22, 2022 at 12:55AM

Q&A: Why eLife Is Doing Away with Rejections

via The Scientist RSS https://ift.tt/jahs7WM The journal's executive director speaks with The Scientist about what it hopes to accomplish with its unusual new publishing model. https://ift.tt/3NzngGP October 21, 2022 at 11:22PM

High-Resolution CAR T Cell Analysis 

via The Scientist RSS https://ift.tt/rdgjO5n Researchers reduce therapeutic CAR T cell heterogeneity with targeted single-cell transcriptomics. https://ift.tt/3NzngGP October 21, 2022 at 08:56PM

Single-Cell Spatial Transcriptomics with Cleavable Fluorescent Probes  

via The Scientist RSS https://ift.tt/PAiuJCY In this webinar, Jia Guo discusses the basics of in situ hybridization and how to use novel fluorescent probes for ultra-sensitive single-cell resolution in situ genomics. https://ift.tt/3NzngGP October 21, 2022 at 08:26PM

Mammalian Oocytes Store mRNA in Newly Found Membraneless Structure

via The Scientist RSS https://ift.tt/z89IU53 The findings answer the longstanding question of where these cells hold the mRNA needed to cope with the transcriptional halt preceding meiosis. https://ift.tt/M1mQtl5 October 21, 2022 at 12:50AM

Genes that Aided Black Death Survival Linked to Autoimmunity

via The Scientist RSS https://ift.tt/x32jzHp A new study points to repercussions of the Medieval pandemic for the health of modern humans. https://ift.tt/M1mQtl5 October 20, 2022 at 11:50PM

Black and Gray Wolf Pairings Stem Disease, Stabilize Population: Study

via The Scientist RSS https://ift.tt/5SM7JQi The black fur allele has fitness costs but also confers higher immunity against canine distemper virus, making mix-and-match mating key to population survival. https://ift.tt/M1mQtl5 October 20, 2022 at 11:00PM

Researchers Report Decoding Thoughts from fMRI Data

via The Scientist RSS https://ift.tt/NgpxF5d A method appears to be the first to noninvasively reconstruct language from brain activity. https://ift.tt/M1mQtl5 October 20, 2022 at 09:00PM

Making Next-Generation Sequencing Easier  

via The Scientist RSS https://ift.tt/SDAoEBl Explore the automation revolution in sequencing workflows. https://ift.tt/M1mQtl5 October 19, 2022 at 08:03PM

Brush Up: Tissue Engineering and Regenerative Medicine

via The Scientist RSS https://ift.tt/htjxCQD A new frontier in repairing organ damage https://ift.tt/H6BZsAi October 17, 2022 at 10:37PM

Ethanol-Making Microbe Tied to Nonalcoholic Fatty Liver Disease

via The Scientist RSS https://ift.tt/pYcf7VW A study adds to evidence linking gut bacteria to liver conditions in people who don't drink excessive amounts of alcohol.  https://ift.tt/H6BZsAi October 19, 2022 at 10:49PM

Methylation in Young Brains May Be Key to Obesity: Mouse Study

via The Scientist RSS https://ift.tt/tvXdU8N Epigenetic events, such as methylation, during early brain development in mice occur in genomic regions associated with BMI in humans, according to a new study. https://ift.tt/H6BZsAi October 19, 2022 at 08:30PM

Methylation Sequencing in Cancer Detection 

via The Scientist RSS https://ift.tt/7eWTh1C Discover how efforts to uncover the genome's methylation patterns advance cancer detection. https://ift.tt/H6BZsAi October 19, 2022 at 12:14AM

Is a Winter COVID-19 Case Surge Coming?

via The Scientist RSS https://ift.tt/f5l4kqm Low booster rates and immune-evading SARS-CoV-2 variants could spell bad news, experts say.  https://ift.tt/gTY7shw October 18, 2022 at 01:24AM

Harboring Hard and Soft Cells Lets Tumors Grow and Metastasize Simultaneously

via The Scientist RSS https://ift.tt/e0QFw5B Islands of rigid cells within a matrix of soft ones allow tumors to be both solid and fluid, granting them toughness without losing the ability to break apart.  https://ift.tt/gTY7shw October 18, 2022 at 12:37AM

Quantify Biomolecules Across Sample Types with ELISAs 

via The Scientist RSS https://ift.tt/5KPWe8M Scientists choose ELISAs for optimal sensitivity, specificity, accuracy, and reproducibility. https://ift.tt/gTY7shw October 17, 2022 at 10:15PM

Mitochondrial DNA Sneaks into Nuclear Genome

via The Scientist RSS https://ift.tt/j1NCsaF Genetic material pilfered from mitochondria may seal cracks in our genetic code, a study suggests. https://ift.tt/gTY7shw October 17, 2022 at 11:23PM

Tissue Engineering and Regenerative Medicine: A New Frontier in Repairing Organ Damage

via The Scientist RSS https://ift.tt/ErveiaC https://ift.tt/gTY7shw October 17, 2022 at 10:37PM

Book Excerpt from The Creative Lives of Animals

via The Scientist RSS https://ift.tt/SKrqVyp In the book's introduction, author Carol Gigliotti makes the case that intricate behavioral patterns can be just as important to conserve as species’ genomes. https://ift.tt/gTY7shw October 17, 2022 at 10:05PM

Automated Pipetting for Effortless DNA Library Normalization  

via The Scientist RSS https://ift.tt/fjAPxrN How robotics and automation provide a streamlined, consistent, and precise solution. https://ift.tt/gTY7shw October 14, 2022 at 11:29PM

New Gene Mutants Identified in Rare Motor Neuron Diseases

via The Scientist RSS https://ift.tt/erI5j6O The discovery of gene variants in cases of hereditary spastic dysplasia could provide a diagnosis to affected families where no genetic cause could be found before. https://ift.tt/gTY7shw October 17, 2022 at 09:30AM

European Medicines Agency Recommends Approving Takeda’s Dengue Vaccine

via The Scientist RSS https://ift.tt/xn1NwlW In clinical trials, the new inoculation demonstrated greater protection for children and people older than 45 than the existing dengue vaccine. https://ift.tt/DCPQKoe October 15, 2022 at 01:32AM

Laboratory Ergonomics for the Whole Human 

via The Scientist RSS https://ift.tt/3Yv4eiu In this webinar, Melissa Afterman and Meg Honan will discuss the importance of ergonomic design for worker wellbeing and maximizing performance. https://ift.tt/DCPQKoe October 14, 2022 at 09:19PM

How Fat Cells Help Kick Parasites Out of Mice: Study

via The Scientist RSS https://ift.tt/utEOdG1 Immune cells get a lot of shine when it comes to fighting infection, but it turns out that fat might be just as important for removing parasitic invaders. https://ift.tt/DCPQKoe October 14, 2022 at 11:30PM

New MRI Technique Tracks Brain Activity at Millisecond Timescales 

via The Scientist RSS https://ift.tt/poDMNsf The method, dubbed "DIANA," could transform neuroscientists' understanding of how the brain works, researchers say—though for now, it’s only been tested in anesthetized mice. https://ift.tt/DCPQKoe October 14, 2022 at 09:45PM

Scientists Resurrect Ancient Rubiscos to Understand Their Evolution

via The Scientist RSS https://ift.tt/9d6s8uc A team proposes that the addition of a small accessory subunit to the carbon-fixing enzyme was key to improving its catalytic properties and specificity to CO2. https://ift.tt/UMycsFw October 14, 2022 at 07:49PM

Severe Drought, Heat Upended Research This Summer

via The Scientist RSS https://ift.tt/ncgw9PE Researchers scramble to adapt as bouts of severe heat and aridity increasingly become the norm. https://ift.tt/UMycsFw October 14, 2022 at 01:58AM

Fred Hutch Receives $710 Million Gift from the Bezos Family

via The Scientist RSS https://ift.tt/FJvh9SX The donation will fund recruitment, research facilities, clinical research, and immunotherapy research. https://ift.tt/UMycsFw October 13, 2022 at 11:05PM

Tackling severe disease with INTEGRA Biosciences electronic pipettes

via The Scientist RSS https://ift.tt/kOzdGeP Researchers at the University of Ostrava, Czech Republic, are using a 12 channel 50μl VOYAGER adjustable tip spacing pipette and ECO Rack GripTip pipette tips from INTEGRA Biosciences to study the role of protein-DNA interactions in the progression of severe diseases, such as cancers and neurodegeneration.  https://ift.tt/UMycsFw October 13, 2022 at 10:43PM

A Novel High-Throughput Screening Assay for Identifying Anticancer Lead Compounds 

via The Scientist RSS https://ift.tt/7uo2UyO The Transcreener dAMP Exonuclease Assay reliably locates compounds that antagonize TREX1. https://ift.tt/UMycsFw October 13, 2022 at 08:26PM

Validating Assays in Flow Cytometry: Learn from the Creators of CLSI Guideline H62

via The Scientist RSS https://ift.tt/GeF3nRB In this webinar, Virginia Litwin, Steve Eck, and Nicolas Bailly will discuss key aspects of the Clinical and Laboratory Standards Institute’s Guideline H62, and how these directives streamline flow cytometry workflows. https://ift.tt/UMycsFw October 11, 2022 at 07:55PM