Skip to main content

Posts

Showing posts from December, 2022

Our Favorite Neuroscience Stories of 2022

via The Scientist RSS https://ift.tt/MGpKHBc This year, neuroscience researchers made important discoveries related to how neurodegeneration attacks the human brain, hooked cultured neurons up to machinery to teach them to play a video game, and more. https://ift.tt/l3vRHbm December 28, 2022 at 10:30PM

Our Favorite Cancer Stories of 2022

via The Scientist RSS https://ift.tt/0DWuS7q This year, cancer researchers uncovered a variety of ways that tumors can survive and spread, ranging from damaging their own DNA to exploiting the nearby microenvironment for nutrients. https://ift.tt/IaSUZon December 27, 2022 at 10:30PM

Remembering Those We Lost in 2022

via The Scientist RSS https://ift.tt/It2BW4d A look at some noteworthy scientists who died this year, leaving behind a legacy of research excellence. https://ift.tt/IaSUZon December 27, 2022 at 01:47AM

Opinion: Universities Must Incentivize Field-Based Research as an Equity Issue

via The Scientist RSS https://ift.tt/oJQDKET Female and minority-identifying researchers face extra challenges in becoming field project leaders. Universities should be providing equivalent numbers of solutions. https://ift.tt/7PBVDAk December 23, 2022 at 03:55AM

Training the Immune System to Fight Chronic Diseases

via The Scientist RSS https://ift.tt/CHfWVGU Learn how naturally regulated N-linked glycan variations influence IgG effector functions. https://ift.tt/7PBVDAk December 21, 2022 at 08:50PM

Our Favorite Genetics Stories of 2022

via The Scientist RSS https://ift.tt/QZJUhvN This year’s stories highlight the expanding versatility of genetic techniques and the increasing utility of such research in all life science fields. https://ift.tt/7PBVDAk December 22, 2022 at 08:30PM

Genome Spotlight: Fishing cat (Prionailurus viverrinus)

via The Scientist RSS https://ift.tt/bEAXnxC A high-quality reference genome for this vulnerable feline may help scientists understand why they’re so prone to transitional cell carcinoma in captivity. https://ift.tt/7PBVDAk December 22, 2022 at 07:30PM

The Top Retractions of 2022

via The Scientist RSS https://ift.tt/aFLg3Wb From typo-laden code in psychedelics research to paper mills and plagiarism, we look back on some of the most notable retractions in scientific publishing this year. https://ift.tt/7PBVDAk December 22, 2022 at 07:00PM

Male and Female Stem Cells Derived from One Donor in Scientific First

via The Scientist RSS https://ift.tt/xYCELBJ Studying otherwise identical XY, XX, X0, and XXY pluripotent stem cells will allow researchers to investigate sex-based differences in greater depth. https://ift.tt/7PBVDAk December 22, 2022 at 06:30PM

Training the Immune System to Fight Chronic Diseases

via The Scientist RSS https://ift.tt/g2et3fu https://ift.tt/FzM4mDy December 21, 2022 at 08:50PM

University of California, Striking Workers Unions Reach Tentative Deal

via The Scientist RSS https://ift.tt/AjzKTMq The agreement, which is not yet ratified, would increase academic workers’ salaries, but some call for an ongoing strike as the raises are less than desired. https://ift.tt/FzM4mDy December 20, 2022 at 11:43PM

PBMCs: Mononucleated and Multipurposed

via The Scientist RSS https://ift.tt/HmvqcAd Researchers employ peripheral blood mononuclear cells (PBMCs) in clinical and academic applications related to the immune system and regenerative medicine. https://ift.tt/79UMgVZ December 16, 2022 at 07:07PM

Using Single-Cell Functional Analysis to Identify Cellular Drivers of Pathology

via The Scientist RSS https://ift.tt/PtqmT0X How single-cell secretomic analysis revealed the role of TEMRA CD8+ T cells in kidney transplant rejection. https://ift.tt/79UMgVZ December 16, 2022 at 02:42AM

“Smarter” CAR T Cells Target Tumors with Precision

via The Scientist RSS https://ift.tt/8lPi65b Two studies in mice now show that researchers can control when and where CAR T cells are active, potentially overcoming previous hurdles for CAR T-based treatments. https://ift.tt/B5eiQsq December 17, 2022 at 02:45AM

Mice With a Healthy Gut Microbiome Are More Motivated to Exercise

via The Scientist RSS https://ift.tt/RMdk4KB A neural pathway between the gut and the brain led to the release of dopamine when the mice ran on a wheel or treadmill, but only in the presence of a robust microbiome.  https://ift.tt/B5eiQsq December 17, 2022 at 01:27AM

Generating Mini-Guts for Drug Screening

via The Scientist RSS https://ift.tt/IPdyQ3w Human gut organoids facilitate precise disease modeling and power high-throughput drug development efforts. https://ift.tt/qsm3o20 December 16, 2022 at 08:51PM

How Do Neurons Work?

via The Scientist RSS https://ift.tt/WMsB6fQ Neurons transmit information through the body via chemical signals and electrical impulses. https://ift.tt/qsm3o20 December 16, 2022 at 01:09AM

Generating Mini-Guts for Drug Screening

via The Scientist RSS https://ift.tt/IPdyQ3w https://ift.tt/qsm3o20 December 16, 2022 at 08:51PM

Specialized Sperm Ribosomes Are Key to Male Fertility in Mice

via The Scientist RSS https://ift.tt/SN2bmOr A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes. https://ift.tt/qsm3o20 December 16, 2022 at 03:37AM

Brush Up: How Do Neurons Work?

via The Scientist RSS https://ift.tt/WMsB6fQ https://ift.tt/qsm3o20 December 16, 2022 at 01:09AM

Mapping Tool Reveals Microglia's Shape-Shifting Secrets

via The Scientist RSS https://ift.tt/qjcSehQ The approach could help test hypotheses about how atypical function of the brain’s immune cells contributes to autism. https://ift.tt/F0GI2sf December 14, 2022 at 10:30PM

Notable Science Quotes

via The Scientist RSS https://ift.tt/qbgiTyf Leaving Twitter, improving science communication, understanding the dangers of avian flu, and more https://ift.tt/1GUAB92 December 14, 2022 at 10:30AM

Snakes Have Clitorises After All, Study Finds

via The Scientist RSS https://ift.tt/GvdFzHJ Researchers visualize the snake clitoris in detail for the first time, finding evidence that the organ may be evolutionarily important for snake sex. https://ift.tt/1GUAB92 December 14, 2022 at 05:31AM

Bringing Fluency to Clinical Diagnostics Through Automation 

via The Scientist RSS https://ift.tt/f4ylDqS Automated liquid handling workstations offer flexibility for a wide range of application and process needs. https://ift.tt/1GUAB92 December 08, 2022 at 12:09AM

Understanding the Blood Cancer Genomic Landscape 

via The Scientist RSS https://ift.tt/qKmO6zi Information about the genomic and immunological characteristics of blood cancers is helping scientists discover and develop new immunotherapies. https://ift.tt/1GUAB92 December 13, 2022 at 08:44PM

Silent Synapses May Provide Plasticity in Adulthood

via The Scientist RSS https://ift.tt/z2kDBZQ Inactive synapses--found on tiny neuronal projections called filopodia--are abundant in the adult brain, a mouse study suggests. https://ift.tt/1GUAB92 December 13, 2022 at 08:05PM

Viral Protein Behind Chronic Inflammation in People with HIV: Study

via The Scientist RSS https://ift.tt/LR6fVzE The HIV protein Nef can cause long-term genetic changes that lead to hyperreactive immune cells, according to research in human cells and mice.  https://ift.tt/tHQm1IM December 12, 2022 at 10:58PM

It’s All in the Timing: Optimizing Chemotherapy Administration

via The Scientist RSS https://ift.tt/Aka4rCT https://ift.tt/tHQm1IM December 12, 2022 at 08:31PM

ApoA1 Identified as a Novel Target for ALS Therapy

via The Scientist RSS https://ift.tt/rvG9Oz4 Researchers found that the ApoA1 protein can restore ALS epithelial cell survival in vitro. https://ift.tt/tHQm1IM December 12, 2022 at 07:30PM

Caught on Camera

via The Scientist RSS https://ift.tt/LqSVD01 See some of the coolest images recently featured by The Scientist. https://ift.tt/tHQm1IM December 12, 2022 at 10:30AM

Study of Millions Finds Genetic Links to Smoking and Drinking 

via The Scientist RSS https://ift.tt/wM9jESI In the largest study of its kind, scientists find nearly 4,000 genetic variants that may predispose people to alcohol and tobacco use behaviors.  https://ift.tt/lhSEF1X December 10, 2022 at 03:10AM

Study Traces a Neural Circuit Behind Green Light-Mediated Pain Relief

via The Scientist RSS https://ift.tt/K3xXUnL A mouse study concludes color-detecting cones in the eye and a subset of neurons in the brain’s thalamus are why green light exposure has an analgesic effect. https://ift.tt/lhSEF1X December 10, 2022 at 01:35AM

Ketamine Flips a “Switch” in Mice’s Brain Circuitry: Study

via The Scientist RSS https://ift.tt/uAT71JR After injecting moderate doses of the dissociative anesthetic into the animals, previously “awake” brain cells go dark, and those that had been dormant suddenly light up. https://ift.tt/lhSEF1X December 09, 2022 at 11:00PM

Opinion: Harnessing Microglia Cells to Stave Off Neurodegenerative Disease

via The Scientist RSS https://ift.tt/kR9VjAF Dialing up the activity of a protein called SYK in the brain's "janitors" could provide an avenue to treat Alzheimer’s and other neurodegenerative diseases. https://ift.tt/LHWor5Q December 09, 2022 at 02:38AM

Cell Culture Conquests: Finding and Defeating the Invisible Enemy

via The Scientist RSS https://ift.tt/FouybiX Cutting-edge reagents, kits, and techniques provide a robust solution to cell culture mycoplasma contamination. https://ift.tt/LHWor5Q December 08, 2022 at 07:27PM

Building Cancer Models with Creative Collaborators

via The Scientist RSS https://ift.tt/Ppan2Al Jennifer Munson shares how teamwork and collaboration have fostered her research at the intersection of creativity and clinical discovery. https://ift.tt/LHWor5Q December 02, 2022 at 09:05PM

Piecing Together Potential Answers for Bardet-Biedl Syndrome

via The Scientist RSS https://ift.tt/wknAJhP https://ift.tt/LHWor5Q December 08, 2022 at 02:07AM

What Happens When You Catch More than One Virus?

via The Scientist RSS https://ift.tt/FtfdOKY The “tripledemic” shines a spotlight on viral interference, in which one infection can block another. https://ift.tt/1MR3iJd December 07, 2022 at 11:15PM

Get Up to Speed on Laboratory Grown Meat

via The Scientist RSS https://ift.tt/Z1t9XPx A comprehensive guide to cultured lab meat and meat alternatives https://ift.tt/1MR3iJd December 07, 2022 at 07:24PM

How Cold Weather May Help You Catch a Cold

via The Scientist RSS https://ift.tt/URGJOwo Warm nasal cells mount stronger defenses against cold-causing coronaviruses and rhinoviruses than those exposed to cooler temperatures, an in vitro experiment finds. https://ift.tt/1MR3iJd December 07, 2022 at 02:43AM

Beyond Individual Nutrients: Complex Diet and Cancer Connections

via The Scientist RSS https://ift.tt/jVISq49 Scientists develop cancer nutrition guidelines based on research examining how dietary patterns affect cancer risk and prevention. https://ift.tt/1MR3iJd December 06, 2022 at 09:08PM

Multiplex Testing: A Solution to Manage Surge in Respiratory Illnesses as Concerns over “Multi-demic” Rise

via The Scientist RSS https://ift.tt/VpJMXYt Eunsin Bae, M.D discusses multiplex testing and the benefits of Seegene’s Allplex™ SARS-CoV-2/FluA/FluB/ RSV Assay  https://ift.tt/wDb9sOg December 06, 2022 at 09:18PM

The Future of Antibody Discovery for Biotherapeutics

via The Scientist RSS https://ift.tt/gfrq3lw Modern screening methods help usher in a new age of antibody therapeutics.  https://ift.tt/wDb9sOg December 05, 2022 at 08:43PM

Environmental RNA Reveals Heat Stress in Water Fleas

via The Scientist RSS https://ift.tt/hgsio5Z The eRNA detection method could one day be used to catch early warning signs of distress in wild ecosystems.  https://ift.tt/p9NUt3j December 02, 2022 at 11:10PM

Elevate Cellular Assays with Microplate Readers

via The Scientist RSS https://ift.tt/rc5EA98 Scientists combine microplate readers and cell-based assays for high throughput and reduced variability across a variety of applications. https://ift.tt/p9NUt3j December 01, 2022 at 08:42PM

Recently Discovered Virus Family Infects a Human Oral Amoeba

via The Scientist RSS https://ift.tt/1W3n45c Redondoviruses, which have been associated with cases of periodontitis and other diseases, turn out to live inside the amoeba Entamoeba gingivalis. https://ift.tt/p9NUt3j December 02, 2022 at 02:40AM

Closed Cell Processing Systems for Cell Therapy Workflows

via The Scientist RSS https://ift.tt/ewskBVA Closed systems increase cell therapy manufacturing process efficiency. https://ift.tt/p9NUt3j December 01, 2022 at 11:07PM

Breaking Through Big Data Bottlenecks 

via The Scientist RSS https://ift.tt/Wphjx0r Discover how machine learning helps scientists accelerate their research.   https://ift.tt/tCopHNa December 01, 2022 at 07:30PM

A Question of Balance: How the Gut Microbiome Influences Diabetes

via The Scientist RSS https://ift.tt/svGI8Ej The presence of beneficial or detrimental microbes pulls the host toward health or disease. https://ift.tt/tCopHNa December 01, 2022 at 07:30PM

Infographic: Intracellular Bacteria's Tricks for Host Manipulation 

via The Scientist RSS https://ift.tt/ZQARFaY Various microbes, including several human pathogens, hijack the cell's skeleton, membranes, and protein-making machinery to make themselves at home. https://ift.tt/tCopHNa December 01, 2022 at 10:30AM