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Showing posts from October, 2023

Fixing the Problem with Induced Pluripotent Stem Cells

via The Scientist RSS https://ift.tt/0sAUDCz A new strategy prevents reprogramming-induced epigenetic aberrations in human induced pluripotent stem cells. https://ift.tt/oIfjru2 October 31, 2023 at 08:30PM

Unraveling the Mystery of Zombie Genes

via The Scientist RSS https://ift.tt/NYiLUAp Digging into how and why some genes are resurrected after death sounds morbid, but it has practical applications.  https://ift.tt/8yLYKrz October 31, 2023 at 06:30PM

How Vesselon Can Improve the Entire Class of Antibody-Drug Conjugates

via The Scientist RSS https://ift.tt/gCvYkjK Vesselon’s novel co-formulation of gas lipid microspheres and self-assembling liposomes, targeted and activated by commercial ultrasound, would be an ideal adjunct to any of these ADC drugs. https://ift.tt/Q2OTy0Y October 30, 2023 at 11:00PM

qPCR: Driving Wastewater Surveillance for Infectious Disease

via The Scientist RSS https://ift.tt/DiQePaE Natalie Knox and the Public Health Agency of Canada’s National Microbiology Laboratory are helping establish a national qPCR-driven wastewater surveillance network for SARS-CoV-2 and other diseases. https://ift.tt/YWTyXd0 October 30, 2023 at 08:00PM

Stem Cells Breathe New Life into Lungs

via The Scientist RSS https://ift.tt/r1FR9vJ New studies proposed using stem cells to make long-lasting lung grafts. https://ift.tt/C1dfHmM October 30, 2023 at 09:30AM

Synthetic Libraries: Where Science Meets Impact

via The Scientist RSS https://ift.tt/upvFMI8 Find answers to common synthetic biology research questions in this collection of quick educational videos. https://ift.tt/J6rxNmC October 25, 2023 at 01:22AM

Spectral Flow Cytometry: Separating the Fluorophore Rainbow

via The Scientist RSS https://ift.tt/qDLrQVC Spectral flow cytometry separates similarly emitting fluorophores and enabled Kaitlyn Sadtler to construct a 24-color rat panel for immunological analyses. https://ift.tt/Z3v9MdV October 24, 2023 at 09:30AM

Adding Another Dimension to Traditional Immunoassays

via The Scientist RSS https://ift.tt/NZfXSEq With an automated capillary electrophoresis platform, researchers simplify protein analysis while obtaining more information from each sample. https://ift.tt/FNvIVSj October 16, 2023 at 08:29PM

Differentiated Stem Cells Can Kickstart Fertility in Mice

via The Scientist RSS https://ift.tt/7tcF24m Ovarian cells derived from stem cells restore hormones and cells needed to produce pups. https://ift.tt/t6J5McY October 23, 2023 at 09:30AM

Advancing Drug Discovery by Employing Synthetic Biology Tools

via The Scientist RSS https://ift.tt/1JThA0G In this webinar, learn about the origins of artificial gene circuits and how researchers currently use synthetic biology strategies to uncover new drugs.  https://ift.tt/c4aYvbp October 18, 2023 at 07:30PM

Accessible Lateral Flow Assays: Test to Treat, Test to Protect

via The Scientist RSS https://ift.tt/7aXpZQb From development to implementation, Rosanna Peeling discusses the importance of rapid tests for public health. https://ift.tt/xEQe8l9 October 18, 2023 at 08:30PM

Immunohistochemistry: Origins, Tips, and a Look to the Future

via The Scientist RSS https://ift.tt/JVlaINw An essential staining technique with a long history, immunohistochemistry (IHC) is being upgraded for modern research and clinical applications. https://ift.tt/c3oipnU October 18, 2023 at 02:58AM

An Introduction to Metabolomics

via The Scientist RSS https://ift.tt/gKHRDwd As the closest reflection of biological phenotype, metabolomics provides critical information about human health and disease. https://ift.tt/ul7DOfb October 18, 2023 at 12:29AM

Mega Multiplexing for Exploring Diseased Tissues

via The Scientist RSS https://ift.tt/nRqfPsg Researchers at KU Leuven specialize in performing a multiplex immunohistochemistry method that uses conventional antibodies and pathologist-driven data analysis. https://ift.tt/TBqM6G3 October 16, 2023 at 11:30PM

Myo-inositol in Human Breast Milk Improves Brain Connectivity

via The Scientist RSS https://ift.tt/sh9Ozt5 Researchers find that the sugar myo-inositol is abundant early in lactation and increases synapse size and abundance in the developing brain. https://ift.tt/EsxqTiH October 16, 2023 at 08:41PM

New Strategies to Discover Human Disease Genes

via The Scientist RSS https://ift.tt/f3JTo0d Learn how researchers across health-related fields identify and characterize disease-causing genomic variants. https://ift.tt/Gqr7XHZ October 16, 2023 at 06:06PM

Overcoming Cancer Therapy Obstacles With Epitope Editing

via The Scientist RSS https://ift.tt/Q0S32zD Editing epitopes expressed on the surfaces of transplanted hematopoietic stem cells renders them resistant to AML treatments without affecting their critical functions. https://ift.tt/CHfJG0L October 12, 2023 at 11:00AM

Myo-inositol in Human Breast Milk Improves Brain Connectivity

via The Scientist RSS https://ift.tt/RrFY6W2 https://ift.tt/7ko3D1i October 10, 2023 at 08:51PM

The Scientist’s Journal Club: Detecting Nucleic Acids with CRISPR

via The Scientist RSS https://ift.tt/lpLskUg Kuangwen Hsieh will discuss his research understanding CRISPR-based nucleic acid detection assays. https://ift.tt/nZhp6Cd October 10, 2023 at 06:34PM

Sino Biological Announces the Opening of Its New US-Based Center for Bioprocessing

via The Scientist RSS https://ift.tt/cYQDyeC Sino Biological, Inc. (“Sino Biological” or the “Company”), is pleased to announce the formal opening of its new Center for Bioprocessing (C4B) in Houston, Texas USA at Levit Green, adjacent to the world-renowned Texas Medical Center. https://ift.tt/WQ9ZOTc October 09, 2023 at 07:30PM

Unlocking the Clinical Power of Mutational Analysis

via The Scientist RSS https://ift.tt/rzQ57tL https://ift.tt/o8wjfJy October 06, 2023 at 11:56PM

The Scientist’s Journal Club: Olfaction and the Brain

via The Scientist RSS https://ift.tt/F1q3kbL Gonzalo Otazu will discuss how the brain processes smells differently in neurotypical mice compared to a mouse model of autism spectrum disorder. https://ift.tt/9xFz65c October 06, 2023 at 12:04AM

The Scientist’s Journal Club: Olfaction and the Brain

via The Scientist RSS https://ift.tt/iek8jH1 https://ift.tt/DTRp29t October 06, 2023 at 12:04AM

A Snapshot of How Obesity Transforms Fat

via The Scientist RSS https://ift.tt/Gvl4aso Spatial methods reveal immune cell formations in fat during early obesity. https://ift.tt/nwb5Edp October 05, 2023 at 07:00PM

A Machine Learning Tool Uncloaks the Hidden Sources of Cancer Cells

via The Scientist RSS https://ift.tt/NBCmp37 Researchers created a model that uses clinical testing data to locate the primary site of cancer cells with no known origin, likely improving survival. https://ift.tt/4L0VOgM October 05, 2023 at 09:30AM

Nobel Prize in Chemistry for Quantum Dots

via The Scientist RSS https://ift.tt/E8wTLCg Moungi Bawendi, Louis Brus, and Alexei Ekimov were awarded the Nobel Prize for their work on quantum dots, which has applications in electronics and biomedicine. https://ift.tt/i6AcOzr October 05, 2023 at 02:14AM

A Snapshot of How Obesity Transforms Fat

via The Scientist RSS https://ift.tt/32xGlgj https://ift.tt/mvdgzto October 04, 2023 at 08:59PM

Machine Learning for Predicting Glioblastoma Prognosis

via The Scientist RSS https://ift.tt/cq70zBX Researchers integrate scRNA-seq, spatial transcriptomics, and histology imaging data to show that spatial cellular architecture predicts glioblastoma prognosis. https://ift.tt/Km1YaEe October 04, 2023 at 09:30AM

Nobel Prize for Experiments With Light

via The Scientist RSS https://ift.tt/BX9wJiu Anne L’Huillier, Pierre Agostini, and Ferenc Krausz received this year’s Physics award for creating tools for studying the world of electrons, with future applications in medical diagnostics. https://ift.tt/42uaNSq October 03, 2023 at 11:26PM

Directing Superior Reagents for Better PCR Results

via The Scientist RSS https://ift.tt/OerJMAp Directed evolution approaches are creating new reagents to help a tried-and-true technique reach new heights. https://ift.tt/X0UbPoC October 02, 2023 at 09:54PM

Nobel Prize for mRNA Vaccines

via The Scientist RSS https://ift.tt/40bsyz8 Katalin Karikó and Drew Weissman received this year’s Physiology or Medicine award for their work on RNA biology and mRNA-based vaccines. https://ift.tt/sImyxai October 02, 2023 at 11:30PM

Tuning T Cells

via The Scientist RSS https://ift.tt/z91GgZ5 An often overlooked property of the tumor environment shapes T cell function and may improve T cell therapies. https://ift.tt/uNypsd3 October 02, 2023 at 09:30AM