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Showing posts from November, 2023

A New mRNA Malaria Vaccine 

via The Scientist RSS https://ift.tt/dJfy8KQ By targeting resident memory T cells in the liver, a novel mRNA malaria vaccine prevented infection, even in those with prior exposure. https://ift.tt/yTO1QWH November 30, 2023 at 08:35PM

CRISPR Gene Editing: Cas9 and Beyond

via The Scientist RSS https://ift.tt/AvCVbkD Researchers create and improve CRISPR-Cas mediated gene editing technologies based on prokaryotic CRISPR systems and eukaryotic DNA repair mechanisms. https://ift.tt/DlJLeoi November 30, 2023 at 12:53AM

The Art and Science of Synthetic Biology 

via The Scientist RSS https://ift.tt/ILW2OTb Researchers get creative using bacterial bits and pieces to produce synthetic cells for studying cancer. https://ift.tt/h6mIwSH November 27, 2023 at 04:48PM

Detecting the Viral Elephant in the Room

via The Scientist RSS https://ift.tt/48o2pu1 A tornado-like vortex sampling technology detects low levels of SARS-CoV-2 viral particles within minutes. https://ift.tt/n4GKEM5 November 29, 2023 at 09:00PM

Organoids: The New Frontier

via The Scientist RSS https://ift.tt/EWmH5bd Explore the latest in organoid production for studying development, disease, and drug screening. https://ift.tt/aKAGEIv November 23, 2023 at 02:51AM

Epigenetic Changes Drive Cancer 

via The Scientist RSS https://ift.tt/OukT8vL An analysis of almost 700 different tumors revealed that DNA methylation drives tumorigenesis just like genetic mutations do.  https://ift.tt/70IhiaB November 28, 2023 at 09:15PM

Move Over, Proteins! Exploring Lipids in Adaptive Immunity

via The Scientist RSS https://ift.tt/9yfrjNY New research revealed hundreds of lipid antigens that may be recognized by adaptive immune T cells. https://ift.tt/2DLiGQI November 27, 2023 at 09:25PM

Pure Water for the Modern Clinical Laboratory

via The Scientist RSS https://ift.tt/0DsjC5Q Water impurities affect the operation of clinical analyzers and the accuracy and reproducibility of their results.  https://ift.tt/mdur6HW November 21, 2023 at 07:39PM

The Art and Science of Synthetic Biology 

via The Scientist RSS https://ift.tt/WRvPuiT https://ift.tt/CzVoAmZ November 27, 2023 at 04:48PM

How Vesselon Can Improve the Entire Class of Radiopharmaceuticals

via The Scientist RSS https://ift.tt/jRnEQmV Vesselon's microspheres optimize radiopharmaceuticals for targeted treatment, enhancing anti-tumor effects. https://ift.tt/FPiuOWe November 21, 2023 at 07:45PM

A Sticky Situation: Optimizing Cell Culture with Essential Extracellular Matrix Proteins

via The Scientist RSS https://ift.tt/Caow4N7 Pre-mixed attachment factors provide a robust solution to streamlining cell culture workflows. https://ift.tt/MXSHILe November 21, 2023 at 12:24AM

Why Scientists Need to Rethink Their Data Platforms

via The Scientist RSS https://ift.tt/2Tb8yBw Good data management is the first step toward improving scientific outcomes with artificial intelligence and machine learning. https://ift.tt/YQN3lEB November 16, 2023 at 11:51PM

You Are When You Eat

via The Scientist RSS https://ift.tt/zx3At4R Intermittent fasting regulates biological time and improves disrupted sleep in an Alzheimer’s disease model. https://ift.tt/ZPApzYE November 20, 2023 at 10:30AM

A Virus that Generates Electricity 

via The Scientist RSS https://ift.tt/9hmljv7 Melting a bacteriophage’s coat of proteins turns it into a tiny power plant, which could fire up the discovery of new bioengineered devices. https://ift.tt/1SDoXJ2 November 18, 2023 at 01:30AM

Improving Tumor Microenvironment Proteomics Using Spatial Biology

via The Scientist RSS https://ift.tt/3Zlu7dk In this webinar, Thomas Campbell will discuss the cutting-edge capabilities of the CellScape™ platform for advancing spatial proteomic analysis of the tumor microenvironment. https://ift.tt/xVoPaFr November 09, 2023 at 07:30PM

Trust Your Gut: Screening Drugs Using Novel Intestinal Models

via The Scientist RSS https://ift.tt/0Epy9LI Discover how cutting-edge nonclinical in vitro models better recapitulate the human gastrointestinal tract. https://ift.tt/cPzuXd8 November 15, 2023 at 01:34AM

Aging and Cancer

via The Scientist RSS https://ift.tt/0hV7mUR The relationship between aging and cancer is complex, with several shared underlying mechanisms.  https://ift.tt/Mo0fy7A November 14, 2023 at 10:49PM

Aging and Cancer

via The Scientist RSS https://ift.tt/0hV7mUR https://ift.tt/Mo0fy7A November 14, 2023 at 10:49PM

Chasing the Sun

via The Scientist RSS https://ift.tt/Qd9gWbq Sunflowers may use a complex set of molecules to track the sun in the sky. https://ift.tt/iDOEwUT November 14, 2023 at 08:30PM

Improving Data Reliability Through Incubator Monitoring 

via The Scientist RSS https://ift.tt/vZQojIm Discover a guide for optimizing CO2 incubator monitoring. https://ift.tt/aKebycZ November 10, 2023 at 10:04PM

A Double Lock Gates Calcium Signaling

via The Scientist RSS https://ift.tt/RAuYVLT Recent studies settle a debate over how the second messenger NAADP, with no known binding site, evokes calcium release from ion channels.  https://ift.tt/QT0MnrZ November 13, 2023 at 10:30PM

An Updated Approach to mRNA Vaccine Quality Assessment

via The Scientist RSS https://ift.tt/Pt4xcGq Researchers developed and validated a sequencing method for mRNA vaccines, moving the manufacturing field forward by linking established technologies with translational applications. https://ift.tt/WJBr7iX November 13, 2023 at 08:30PM

Newly Developed mRNA Vaccine Protects Against Lyme Disease

via The Scientist RSS https://ift.tt/DLFX49b Leveraging the same mRNA platform used for covid vaccines, researchers generated a vaccine that prevents mice from acquiring Lyme disease. https://ift.tt/Kkxgj3q November 13, 2023 at 08:30PM

A microRNA Family Drives the T Cell Response in Cancer

via The Scientist RSS https://ift.tt/mTxJwhc When their in vitro and in vivo results conflicted, researchers took a deep dive into microRNAs’ influence on T cell memory formation. https://ift.tt/CzUTMDK November 11, 2023 at 10:30AM

Insights into qPCR: Protocol, Detection Methods, and Analysis

via The Scientist RSS https://ift.tt/m7G5eV9 Learn about quantitative PCR (qPCR), including its fundamentals, common applications, modes of detection, and key quantification methods. https://ift.tt/DFOmn3k November 09, 2023 at 01:12AM

Fixing Freezer Failures

via The Scientist RSS https://ift.tt/xGK1YqS Freezer failures can lead to significant sample loss, but researchers can take measures to prevent these events.  https://ift.tt/hcWftnD November 10, 2023 at 02:57AM

Illuminating Organs with Organoids

via The Scientist RSS https://ift.tt/BeDV6NH In this webinar, Benjamin Freedman talks about the importance of organoids in modeling organ function and disease. https://ift.tt/TQmiKzP November 06, 2023 at 10:55PM

The Basics and Applications of Cell-Free DNA 

via The Scientist RSS https://ift.tt/VwvdGzR Found circulating in peripheral blood, scientists use cell-free DNA (cfDNA) to assess genetic abnormalities, infections, cancer, transplant rejection, and cardiovascular disease. https://ift.tt/WyzHGcC November 09, 2023 at 01:51AM

Beyond Skin Deep: Analyzing Melanoma Cells Through Morphology

via The Scientist RSS https://ift.tt/6ShNb1c In this webinar, Evelyn Lattmann will discuss how she examined melanoma cell morphology without labels using an AI-based microscope system.   https://ift.tt/EMGrRVk November 07, 2023 at 09:51PM

The Brain's Barrier Controls Ant Behavior

via The Scientist RSS https://ift.tt/m70cBsO Division of labor in ant colonies may depend on an enzyme trapped inside the blood-brain barrier. https://ift.tt/P2LvNEJ November 08, 2023 at 08:30PM

A New Drug Fixes a Leak Caused by Bacteria

via The Scientist RSS https://ift.tt/eNKJR91 Researchers discovered how virulent bacterial proteins leech nutrients from plant cells, leading to a potential treatment for diseased crops. https://ift.tt/853i1Ha November 08, 2023 at 08:00PM

Comprehensive Quality Control and Interactive Analysis of Single Cell RNA-seq Data

via The Scientist RSS https://ift.tt/n63Ealf In this webinar, Joshua Campbell will talk about the fundamentals of scRNA-seq analysis and how to handle various challenges.  https://ift.tt/eJnwy6k November 07, 2023 at 11:13PM

The Wonderfully Shrunken Cas13

via The Scientist RSS https://ift.tt/pCq6RHG Scientists removed unnecessary sections of the Cas13 enzyme, creating a mini-enzyme that works and fits with other CRISPR elements into a single gene therapy vector. https://ift.tt/ZdsAW3Y November 07, 2023 at 08:00PM

Illuminating Organs with Organoids

via The Scientist RSS https://ift.tt/l2SfNW4 https://ift.tt/sUBSW1V November 06, 2023 at 10:55PM

A Menagerie on a Leaf

via The Scientist RSS https://ift.tt/hO7qv9f A simple rainforest leaf swab revealed DNA from dozens of animal species, possibly improving biodiversity monitoring in the future. https://ift.tt/woZ3d79 November 06, 2023 at 08:00PM

Illuminating the Plant Gene Map

via The Scientist RSS https://ift.tt/PrUyijz PHYTOMap revealed the intricate genetic plant landscape, which helped researchers better understand how cells and gene expression influence each other in three-dimensional space. https://ift.tt/EtOdA8f November 02, 2023 at 10:30PM

Macrophages Curtail Tuberculosis

via The Scientist RSS https://ift.tt/hKbYocD Two autophagy genes work together to stop Mycobacterium tuberculosis dead in its tracks. https://ift.tt/0eA89ij November 01, 2023 at 09:30AM