Skip to main content

Posts

Showing posts from January, 2024

Shake Smarter, Not Harder.

via The Scientist RSS https://ift.tt/8BFi1xK The new OHAUS Endeavor™ Series Light Duty Orbital Shakers set a new standard for precise, intelligent operation. https://ift.tt/J2itEuR January 26, 2024 at 02:10AM

Optimizing Gene Editing with PARP1 CRISPR Plasmids 

via The Scientist RSS https://ift.tt/5QY0zUq CRISPR plasmids provide a robust solution for streamlining human cell transfection workflows.    https://ift.tt/KRUiG4M January 25, 2024 at 01:18AM

Fatty Feasts May Come at an Immune Cost

via The Scientist RSS https://ift.tt/3Apufei Dietary changes rapidly alter T cell metabolism, but the effects can be reversed. https://ift.tt/KtmqOw0 January 25, 2024 at 11:10PM

A Gut Feeling About Parkinson’s Disease

via The Scientist RSS https://ift.tt/CfdZhey CD4 T cells mediate gut symptoms that indicate early Parkinson’s disease. https://ift.tt/wIlRHhq January 25, 2024 at 07:30PM

Standardizing Gut Microbiome Studies

via The Scientist RSS https://ift.tt/Dz8ThaS NIST has spent years developing a human fecal reference material. https://ift.tt/F7Cxzhy January 24, 2024 at 09:30PM

How Plants Protect Their DNA in Space 

via The Scientist RSS https://ift.tt/iCKnuzZ Dorothy Shippen and Borja Barbero Barcenilla investigated how spaceflight affects telomeres of Arabidopsis seedlings grown on the International Space Station. https://ift.tt/uoC85h1 January 24, 2024 at 07:30PM

A Molecular Switch for Bone Loss

via The Scientist RSS https://ift.tt/0G6kPSZ Blocking an abnormally active signaling pathway in skeletal stem and progenitor cells alleviates bone mass decline in middle-aged mice.  https://ift.tt/83BZJkE January 23, 2024 at 07:30PM

Forget Something? You’re Supposed To Do That

via The Scientist RSS https://ift.tt/K42UzV6 Forgetting things appears to be a productive process and not a passive loss of information. https://ift.tt/HLrXZFT January 22, 2024 at 09:30PM

The Problem with Protocols

via The Scientist RSS https://ift.tt/yN7I0ZJ Faced with a lack of consensus in published protocols, researchers found optimal conditions for enhancing cortical neuron adhesion and maturation in culture. https://ift.tt/68ZMCux January 22, 2024 at 06:30PM

Setting Standards for Stool

via The Scientist RSS https://ift.tt/1zm7VFh Microbiome studies have yielded hundreds of ideas for ways to detect and influence human health, but the field struggles with reproducibility challenges that hamper bringing these goals to fruition. Identical tubes of fecal matter should help. https://ift.tt/Q0ecT78 January 19, 2024 at 07:30PM

A Support System for Precision Genomics in Oncology

via The Scientist RSS https://ift.tt/lrVwBKe A novel platform paves the way for genomics-based oncology testing, with a knowledgebase of actionable biomarkers and help for scientists developing in-house tests. https://ift.tt/FBErWHw January 16, 2024 at 07:48PM

Using Brain Organoids in Human Health and Disease Research

via The Scientist RSS https://ift.tt/aLfAGX7 Learn how scientists across life science and engineering disciplines join forces to build brain organoids that mimic neurodevelopment. https://ift.tt/CJAHvL3 January 17, 2024 at 11:44PM

Standardized Data Analysis of Multiplex PCR

via The Scientist RSS https://ift.tt/cYFHUD8 Automated analysis minimizes error risk, analysis time, and technician variation. https://ift.tt/x3EbNWL January 16, 2024 at 11:36PM

Bugs as Drugs to Boost Cancer Therapy

via The Scientist RSS https://ift.tt/fH7j6FN Bioengineered bacteria sneak past solid tumor defenses to guide CAR T cells’ attacks. https://ift.tt/TJDf6RI January 18, 2024 at 07:30PM

Rapidly Characterizing Complex Samples with Mass Photometry

via The Scientist RSS https://ift.tt/Ls3Cm9X In this webinar, Perla Vega and Philip Kitchen will explore how scientists can use mass photometry to assess sample quality and characterize proteins. https://ift.tt/iKAGnmr January 12, 2024 at 11:35PM

Decoding the Cellular Secrets of the Endometrium 

via The Scientist RSS https://ift.tt/drixOUy Endometrial organoids and single cell analyses helped uncover the molecular mechanisms of a rare uterine condition. https://ift.tt/iJFsh6r January 16, 2024 at 07:30PM

Advanced Spatial Tools Map Hematopoietic Stem Cell Niches

via The Scientist RSS https://ift.tt/F1KG2Mx New technologies and archival tissue biopsy samples enable exploration of changes in the bone marrow as people age. https://ift.tt/eIEN8VZ January 15, 2024 at 07:30PM

Charting a New Course Through the Injured Brain

via The Scientist RSS https://ift.tt/6vjFsBa A state-of-the-art technique helps scientists map out tissue at the single cell level after a demyelinating brain injury. https://ift.tt/lPacBM9 January 15, 2024 at 06:30PM

Genotoxic Effects of Base and Prime Editing

via The Scientist RSS https://ift.tt/X9mHMlE A risk-benefit analysis of gene editing tools in stem cells revealed that base and prime editing carry vulnerabilities similar to those of CRISPR-Cas9, but at a reduced rate.  https://ift.tt/EFv4Dlt January 12, 2024 at 07:30PM

Developing a Protocol for Generating Genetically Modified NK Cells

via The Scientist RSS https://ift.tt/KexVfrn Natural killer (NK) cells target infected and oncogenic cells, but are difficult to work with in vitro. Discover novel approaches to producing genetically modified NK cells for cell therapy.  https://ift.tt/rNUyTbP January 09, 2024 at 02:33AM

Building Nerf Gun Blasters from DNA Bricks

via The Scientist RSS https://ift.tt/H7fn1OA Researchers ingeniously repurposed DNA to assemble a miniaturized blaster at the molecular level. https://ift.tt/ADuSsta January 11, 2024 at 07:30PM

The Evolution of Bats’ Super Immunity

via The Scientist RSS https://ift.tt/ctqz8rb Researchers generated complete genomes of two important bat species and explored their immune- and cancer-related genes. https://ift.tt/g1Ksrv5 January 10, 2024 at 07:30PM

Clues in the Coprolites

via The Scientist RSS https://ift.tt/9Ofn15b Fossilized feces help scientists understand the lives of Puerto Rico’s earliest inhabitants. https://ift.tt/plrYEtH January 09, 2024 at 07:30PM

New Strategies in the Battle Against Infectious Diseases

via The Scientist RSS https://ift.tt/IfT0AJN Learn how the latest research into viral and bacterial pathogens advances the prevention and treatment of infectious diseases.  https://ift.tt/kxtLq4h January 09, 2024 at 01:21AM

Shedding Light on Cell Attachment

via The Scientist RSS https://ift.tt/pxWZ3OK Cell adhesion may be initiated by small proteins previously viewed as helpers, not main players in attachment. https://ift.tt/Vo34qkh January 08, 2024 at 07:30PM

fgf

via The Scientist RSS https://ift.tt/x4zpunJ https://ift.tt/KD51inG January 06, 2024 at 12:21AM

Beyond Cytotoxicity: The Importance of T Cell Memory

via The Scientist RSS https://ift.tt/ayrdm51 In this webinar, Grégoire Lauvau and Marcus Buggert will discuss the function and role of memory T cells in health and disease. https://ift.tt/dFS5A4E January 04, 2024 at 11:46PM

All-nighters Sometimes Combat Depression

via The Scientist RSS https://ift.tt/O4MpsbB Dopamine pathways play a key role in the surprising effects of sleep deprivation on mood. https://ift.tt/OfWrzeG January 05, 2024 at 07:30PM

Beyond Cytotoxicity: The Importance of T Cell Memory

via The Scientist RSS https://ift.tt/HDgVL7W https://ift.tt/L3CwAbJ January 04, 2024 at 11:46PM

The COVID-19 Pandemic Abruptly Altered the Infant Microbiome

via The Scientist RSS https://ift.tt/6ba5Igm Microbial diversity in the infant gut shrank suddenly during the first lockdown, but the lasting health effects are less clear. https://ift.tt/y7h6mQu January 04, 2024 at 07:30PM

Hijacking Neurons’ Adaptive Abilities

via The Scientist RSS https://ift.tt/nSbslk5 Brain tumors use the brain’s plasticity to promote their own growth. https://ift.tt/i8qCjfo January 03, 2024 at 09:00PM

An Overview of High Throughput Screening

via The Scientist RSS https://ift.tt/gRNQyzt High throughput screening (HTS) relies on liquid handling devices, robotics, plate readers, and data processing software to automatically test a large number of biological, genetic, chemical, or pharmacological samples.  https://ift.tt/jaonBqY December 30, 2023 at 12:17AM

Analyzing Phantom Spectra

via The Scientist RSS https://ift.tt/5Po02te Katarzyna Tych wants to normalize failure as part of the scientific process. https://ift.tt/BvztX0V January 01, 2024 at 10:30AM